Up-to-date experience with the international classification system Bethesda 2010 for thyroid fine-needle aspirate: a review

Česká verzia

Authors: Marie Ludvíková ^1,2; Ivana Kholová ³
Authors place of work: Ústav biologie LF UK Plzeň ¹; Ústav patologie 1. LF UK a VFN Praha ²; Patologie, Fimlab Laboratoře, Univerzitní nemocnice v Tampere, Tampere, Finsko ³
Published in the journal: Čes.-slov. Patol., 50, 2014, No. 3, p. 155-160
Category: Přehledový článek

Summary

The Bethesda System for Reporting Thyroid Cytopathology (BSRTC) was introduced in thyroid fine needle aspiration cytology (FNAC) in 2010. A six-tier system is generally accepted. Bethesda categories include morphologic description, risk of malignancy and follow-up suggestions in each group. The system has its advantages and disadvantages, that are discussed. The most problematic are the categories of „Atypia of undetermined significance“ or „Follicular lesion of undetermined significance“ (AUS/FLUS). The group is heterogenous and overused thus far. The possibilities of its improvement are discussed. The Bethesda system does not include any prognostic and predictive markers. However, they represent the promising direction in the improved version of the BSRTC. Novel molecular methods and alternative techniques such as core needle biopsy are briefly discussed.

Keywords:
fine needle aspiration cytology – thyroid gland – Bethesda classification 2010 – benefits - shortcomings

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