POCT system for the fecal calprotectin detection in the tele-monitoring of patients with inflammatory bowel disease

Česká verzia

Authors: K. Malíčková ^1,2; V. Pešinová ¹; M. Kolář ¹ ; M. Lukáš ^1,2
Authors place of work: Klinické a výzkumné centrum pro idiopatické střevní záněty ISCARE IVF a 1. LF UK, Praha ¹; Ústav lékařské biochemie a laboratorní diagnostiky VFN a 1. LF UK, Praha ²
Published in the journal: Klin. Biochem. Metab., 27, 2019, No. 2, p. 72-77

Summary

Objective: To verify the use of home-based CalproSmart fecal calprotectin (FC) test in the telemonitoring of patients with inflammatory bowel disease (IBD).

Design: Retrospective.

Settings: Clinical Centre ISCARE I.V.F. and 1^st Faculty of Medicine of Charles University, Jankovcova 1569/2c, 170 00 Prague 7, Czech Republic.

Material and Methods: Hundred FC values were compared: first data set was measured by patients using the home-based CalproSmart test based on laminar flow analysis (LFA), and the second data set was obtained by the standard fluoroimmunoassay (FIA) in a clinical laboratory.

Results: Spearman’s correlation coefficient r = 0.895 (p = 0.0004) and weighted Cohen’s kappa 0.835 indicates the good correlation of two data sets measured by different measurement systems.

Conclusion: Home-based FC test CalproSmart is well-suited to qualitative FC analysis in telemonitoring of patients with IBD. It cannot replace standard laboratory FC measurements, but this property is not even required by home-based kit.

Keywords:

fecal calprotectin – inflammatory bowel disease – Telemedicine

Zdroje

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