Gastropericardial fistula: getting to the heart of the matter

English version České info

Background:
Gastropericardial fistula is a rare life-threatening condition, being reported only 65 times in modern literature.

Case presentation:
A 67 year-old man who presented with weight loss, chest pain and epigastric pain was found to have pericardial effusion and pneumopericardium on computed imaging. Endoscopy and histology confirmed a gastric adenocarcinoma within a hiatus hernia, which had fistulated to the pericardium. His condition was complicated by pulmonary emboli and lobar infarction, all contributing to rapid deterioration and death.

Conclusion:
Review of all previously published cases reveals that factors which predict poorer prognosis are older age, cancer etiology and conservative management. Conversely, protective factors include younger age at presentation, previous gastroesophageal surgery or ulcers as an etiology, and aggressive procedural and surgical management. Although the diagnosis is viewed as largely fatal by many clinicians, operative management has contributed to a statistically significant reduction in mortality from 69 % in the pre-2000 era to 11 % in the post-2000 era. This study summarizes diagnostic methods and treatment interventions and prognostication in this rare condition.

Keywords:
Gastropericardial fistula, Pneumopericardium, Pericarditis, Gastric adenocarcinoma

Autoři: Vian Azzu ^1,2
Působiště autorů: Hinchingbrooke Hospital, Hinchingbrooke Park, Huntingdon PE 9 6NT, UK ¹; Department of Medicine, University of Cambridge, Hills Road, Cambridge CB2 0QQ, UK ²
Vyšlo v časopise: BMC Gastroenterology 2016, 16:96
Kategorie: Case report
prolekare.web.journal.doi_sk: https://doi.org/10.1186/s12876-016-0510-8

© 2016 The Author(s).

Open access
This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
The electronic version of this article is the complete one and can be found online at: http://bmcgastroenterol.biomedcentral.com/articles/10.1186/s12876-016-0510-8

Souhrn

Background:
Gastropericardial fistula is a rare life-threatening condition, being reported only 65 times in modern literature.

Keywords:
Gastropericardial fistula, Pneumopericardium, Pericarditis, Gastric adenocarcinoma

Zdroje

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