From an old drug to a new one: Synthesis of valproate from 5,5-dipropylbarbituric acid
Autoři:
Oldřich Farsa; Pavol Brka
Působiště autorů:
Department of Chemical Drugs, Faculty of Pharmacy University of Veterinary and Pharmaceutical Sciences, Brno, Czech Republic
Vyšlo v časopise:
Čes. slov. Farm., 2015; 64, 287-288
Kategorie:
44<sup>th</sup> Conference drug synthesis and analysis
Zdroje
1. Addictive Compounds Act No. 167/1998 Coll.
2. Government Regulation Concerning the lists of Addictive Compounds No. 463/2013 Coll.
3. Aspelund H., Skoglund L. The stability of the sodium salts of some soporifics of the barbituric acid series in solution. Acta Acad. Aboensis Math. et Phys. 1937; 10, 14–36.
4. Mokrosz J., Bojarski J. Hydrolysis of barbituric acid derivatives. Part IV. Hydrolysis of derivatives without a shielding steric effect. Polish Journal of Chemistry 1982; 56, 491–500.
5. Helavi V. B., Solabannavar S. B., Desai U. V., Mane R. B. Microwave assisted hydrolysis of Meldrum’s acid derivatives and decarboxylation of derived malonic acids. J. Chem. Research (S), 2003; 2003, 174–175.
6. Toussaint O., Capdevielle P., Maumy M. The Copper(I)-Catalyzed Decarboxylation of Malonic Acids; A New Mild and Quantitative Method. Synthesis 1986; 1986. 1029–1031.
7. Barton H., Mokrosz J., Bojarski J., Klimczak M. Photochemical degradation of barbituric acid derivatives. Part 1. Products of photolysis and hydrolysis of pentobarbital. Pharmazie 1980; 35, 155–158.
Štítky
Farmácia FarmakológiaČlánok vyšiel v časopise
Česká a slovenská farmacie
![Číslo 6](https://www.prelekara.sk/media/cache/resolve/journal_issue/media/image_pdf/2a2df3b5dcd04ccbbe31a843da1e0793.jpeg)
2015 Číslo 6
Najčítanejšie v tomto čísle
- Antibakteriální účinky přírodních látek – silice
- Povrch těla a tělesná hmotnost dospělé české onkologické populace
- Cholinergický systém srdca
- Organická syntéza, Laboratórny manuál