Dercum’s Disease (Lipomatosis Dolorosa) – a Rarely Diagnosed Disease: a Case Study

Česká verzia

Authors: J. Hržičová ¹; S. Jančo ¹; B. Kollár ¹; F. Ondriaš ²; P. Turčáni P ¹
Authors place of work: I. neurologická klinika LF UK a FNsP, Bratislava ¹; Oddelenie patológie, FNsP Bratislava, pracovisko Ružinov ²
Published in the journal: Cesk Slov Neurol N 2007; 70/103(6): 707-709
Category: Kazuistika

Summary

Dercum’s disease is a rare condition characterized by development of painful subcutaneous fatty tissue deposits. The etiology remains unknown. Genetic factors, autoimmune mechanisms, microcirculation disturbances as well as alteration in lipid and carbohydrate metabolism are under the consideration. Typically postmenopausal obese women in age 35–50 years are affected. The most characteristic symptom is generalized or local pain of subcutaneous fatty tissue deposits often associated with asthenia, weakness, fatigability and mental disturbances, including emotional instability, depression, confusion and dementia. Diagnosis is made purely clinically and therapy is only symptomatic. To improve quality of life of affected individual combination of medications, surgery and psychiatric care is necessary. Presented case report should draw attention to this rarely diagnosed clinical condition.

Key words:
Dercum’s disease – lipomatosis dolorosa

Zdroje

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