EEG MICROSTATES ANALYSIS IN PATIENTS WITH EPILEPSY

English version

Autoři: Vaclava Piorecka ^1,2; Marek Piorecký ^1,2; Jan Strobl ^1,2; Marie Nezbedova ¹; Hana Schaabova ¹; Vladimir Krajca ¹
Vyšlo v časopise: Lékař a technika - Clinician and Technology No. 3, 2018, 48, 96-102
Kategorie: Original research

Souhrn

Analysis of microstates in electroencephalographic recordings (EEG) is a promising topographical method that is currently being studied for the diagnosis of neuropsychiatric diseases. The aim of our study is to describe the feasibility of using the microstate analysis of EEG for examination of the epileptic patients. The EEG recordings were measured on patients with epilepsy and on control subjects (with no epileptic pathology). We calculated the global field power (GFP) curve to extract microstates from the EEG recordings. We took local maxima (peaks) of GFP curve to create amplitude topographic maps. Four microstates can be found or are proven to be found in physiological activity, sleeping, and in some pathological activity (schizophrenia). Our goal is to find out if the same microstates also occur in patients with epilepsy. Our assumption is that, if all four identical microstates are present in EEG with epileptic activity, the parameters of these microstates should differ between the EEG of a healthy individual and a person suffering from epilepsy. We observed that the microstate 1 seems to have a higher occurrence for the non-epileptic controls than the patients with epilepsy. The duration of the microstate 4 seems to be higher in the epileptic patients than the non-epileptic controls. We have found that there is a significant difference in the duration, occurrence and contribution of the amplitude topographic maps between the non-epileptic controls and the patients with epilepsy.

Keywords:

EEG, Microstates, GFP, Epileptic activity

Zdroje

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