EEPD1: Breaking and Rescuing the Replication Fork

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Vyšlo v časopise: EEPD1: Breaking and Rescuing the Replication Fork. PLoS Genet 12(2): e32767. doi:10.1371/journal.pgen.1005742
Kategorie: Perspective
prolekare.web.journal.doi_sk: https://doi.org/10.1371/journal.pgen.1005742

Souhrn

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Zdroje

1. Zeman MK, Cimprich KA (2014) Causes and consequences of replication stress. Nat Cell Biol 16: 2–9. doi: 10.1038/ncb2897 24366029

2. Cortez D (2015) Preventing replication fork collapse to maintain genome integrity. DNA Repair (Amst) 32: 149–157.

3. Mazouzi A, Velimezi G, Loizou JI (2014) DNA replication stress: causes, resolution and disease. Exp Cell Res 329: 85–93. 25281304

4. Allen C, Ashley AK, Hromas R, Nickoloff JA (2011) More forks on the road to replication stress recovery. J Mol Cell Biol 3: 4–12. doi: 10.1093/jmcb/mjq049 21278446

5. Wu Y, Lee S-H, Williamson EA, Reiner BL, Cho JH, et al. (2015) EEPD1 rescues stressed replication forks and maintains genome stability by promoting end resection and homologous recombination repair. PLoS Genet 11(12): e1005675. doi: 10.1371/journal.pgen.1005675 26684013

6. Thangavel S, Berti M, Levikova M, Pinto C, Gomathinayagam S, et al. (2015) DNA2 drives processing and restart of reversed replication forks in human cells. J Cell Biol 208: 545–562. doi: 10.1083/jcb.201406100 25733713

7. Nimonkar AV, Genschel J, Kinoshita E, Polaczek P, Campbell JL, et al. (2011) BLM- DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair. Genes Dev 25: 350–362 doi: 10.1101/gad.2003811 21325134

Štítky

Genetika Reprodukčná medicína

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PLOS Genetics

2016 Číslo 2

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Autori: MUDr. Tomáš Ürge, PhD.

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