Colonic perforation in patients with COVID-19 pneumonia – case reports

Česká verzia

Authors: M. Filová; Z. Adamová
Authors place of work: Chirurgické oddělení, Vsetínská nemocnice, a. s.
Published in the journal: Rozhl. Chir., 2021, roč. 100, č. 7, s. 353-356.
Category: Kazuistika
doi: https://doi.org/10.33699/PIS.2021.100.7.

Summary

Introduction: Gastrointestinal complications in critically ill patients during the COVID-19 pandemic pose a diagnostic and treatment dilemma.

Case report: We present two cases of SARS-CoV-2 positive patients treated in our department for colon perforation. One patient was operated for a diastasic right colon perforation due to acute over distension of the bowel. The perforation in the second case was associated with chronic diverticulitis.

Conclusion: These cases highlight the fact that besides typical respiratory symptoms and signs of COVID-19, digestive symptoms also occur. These can caused by intestinal perforation, be it directly or due to changing homeostasis of the internal environment.

Keywords:

COVID-19 – spontaneous colon perforation – stercoral peritonitis

Zdroje

Qi F, Qian S, Zhang S, et al. Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses. Biochem Biophys Res Commun. 2020;526(1):135−140. doi: 10.1016/j.bbrc.2020.03.044.
Cai J, Xu J, Lin D, et al. A case series of children with 2019 novel coronavirus infection: clinical and epidemiological features. Clin Infect Dis. 2020 Sep 12;71(6):1547−1551. doi: 10.1093/cid/ciaa198.
Zhang W, Du R-H, Li B, et al. Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes. Emerg Microbes Infect. 2020;9:386–389. doi: 10.1080/22221751.2020.1729071.
Wang D, Hu B, Hu C, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA 2020;323(14):1406−1407.doi: 10.1001/jama.2020.1585.
Henry BM, de Oliveira MHS, Benoit J, et al. Gastrointestinal symptoms associated with severity of coronavirus disease 2019 (COVID-19): a pooled analysis. Intern Emerg Med. Epub ahead of print 17 April 2020. doi: 10.1007/s11739-020-02329-9.
Lin L, Jiang X, Zhang Z, et al. Gastrointestinal symptoms of 95 cases with SARS-CoV-2 infection. Gut 2020;69(6):997−1001. doi:10.1136/gutjnl-2020-321013.
De Nardi P, Parolini DC, Ripa M, et al. Bowel perforation in a Covid-19 patient: case report. Int J Colorectal Dis. Epub ahead of print 27 May 2020. doi: 10.1007/s00384-020-03627-6.
Kangas-Dick A, Prien C, Rojas K, et al. Gastrointestinal perforation in a critically ill patient with COVID-19 pneumonia. SAGE Open Med Case Rep. 2020;8:2050313X20940570. Published 2020 Jul 16. doi:10.1177/ 2050313X20940570.
Costanzi A, Monteleone M, Confalonieri M, et al. COVID-19 and acute perforated diverticulitis: management and surgical timing. Minerva Chir. 2020 Dec;75(6):468−470. doi: 10.23736/S0026-4733.20.08487-4. Epub 2020 Sep 25.
Schwab K, Hamidi S, Chung A, et al. Occult colonic perforation in a patient with coronavirus disease 2019 after interleukin-6 receptor antagonist therapy. Open Forum Infect Dis. 2020 Sep 12;7(11):ofaa424. doi: 10.1093/ofid/ofaa424.
Almeida Vargas A, Valentí V, Sánchez Justicia C, et al. Severe colon ischemia in patients with severe coronavirus-19 (COVID-19). Rev Esp Enferm Dig. 2020 Oct;112(10):784−787. doi: 10.17235/reed.2020.7329/2020.