Theophylline poisoning – case report and review of literature

Česká verzia

Authors: Zimmer Michal; Šrámek Vladimír; Suk Pavel
Authors place of work: Anesteziologicko-resuscitační klinika, Fakultní nemocnice u svaté Anny v Brně
Published in the journal: Anest. intenziv. Med., 25, 2014, č. 5, s. 360-366
Category: Intesive Care Medicine - Case Report

Summary

A case report and a literature research focused on theophylline intoxication is presented. There is a high risk of theophyllin overdosing due to its narrow therapeutic range. The intoxication can cause a life threatening state requiring adequate treatment. Gastrointestinal and cardiovascular symptoms are the most frequent. Tachyarrhythmias respond to betablockers: titration of intravenous esmolol may be advantageous in a haemodynamically unstable patient. Therapy is directed by symptom severity and theophyline plasma level.

Keywords:
theophylline – intoxication – esmolol

Zdroje

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