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Long‑term Response of Liver Metastases of Breast Cancer to Capecitabine –  Case Report


Authors: D. Macková
Authors place of work: Klinika komplexní onkologické péče, Masarykův onkologický ústav, Brno
Published in the journal: Klin Onkol 2010; 23(1): 46-48
Category: Case Reports

Summary

A case report of a patient with HER2- positive liver metastases of breast cancer. Partial regression was reached during chemotherapy, which was further stabilized by trastuzumab. Resection of the metastases was performed after progression. Capecitabine was started after the occurrence of new multiple lesions; complete regression was reached, which has now lasted over three years with continued capecitabine treatment.

Key words:
breast cancer –  liver metastases


Zdroje

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2. Carlini M, Lonardo MT, Carboni F et al. Liver metastases from breast cancer. Results of surgical resection. Hepatogastroenterology 2002; 49(48): 1597– 1601.

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5. Miles D, Vukelja S, Moiseyenko JA et al. Survival benefit with capecitabine/ docetaxel versus docetaxel alone: Analysis of therapy in a randomized phase III trial. Clinical Breast Cancer 2004; 5(4): 273– 278.

6. Verma S, Wong NS, Trudeau M et al. Survival Differences Observed in Metastatic Breast Cancer Patients Treated With Capecitabine When Compared With Vinorelbine After Pretreatment With Anthracycline and Taxane. Am J Clin Oncol 2007; 30: 297– 302.

7. von Minckwitz G, du Bois A, Schmidt M et al. Trastuzumab beyond progression in human epidermal growth factor receptor 2- positive advanced breast cancer: a german breast group 26/ breast international group 03– 05 study. J Clin Oncol 2009; 27(12): 1999– 2006.

8. Cameron D, Casey M, Press M et al. A phase III randomized comparison of lapatinib plus capecitabine versus capecitabine alone in women with advanced breast cancer that has progressed on trastuzumab: updated efficacy and bio­marker analyses. Breast Cancer Res Treat 2008; 112(3): 533– 543.

Štítky
Paediatric clinical oncology Surgery Clinical oncology

Článok vyšiel v časopise

Clinical Oncology

Číslo 1

2010 Číslo 1
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