Positron Emission Tomography in the Diagnosis and Monitoring of Patients with Nonseminomatous Germ Cell Tumours

Česká verzia

Authors: T. Büchler ¹; K. Šimonová ²; P. Fencl ²; J. Abrahámová ¹
Authors place of work: Onkologické oddělení, Fakultní Thomayerova nemocnice a 1. LF UK, Praha ¹; Oddělení nukleární medicíny a PET centrum, Nemocnice Na Homolce, Praha ²
Published in the journal: Klin Onkol 2011; 24(6): 413-417
Category: Reviews

Summary

The role of 18-fluorodeoxyglucose positron emission tomography (FDG-PET) in the diagnosis and monitoring of nonseminomatous germ cell tumours is currently unclear. Clinical studies have suggested that FDG-PET has relatively low sensitivity and specificity in the setting of initial staging and viability assessment of post-chemotherapy residual lesions. On the other hand, FDG-PET provides potentially useful information in patients with elevated tumour markers and/or multiple residual lesions with limited resectability. Other possible indications of FDG-PET are the early assessment of tumour chemosensitivity and the diagnosis of inflammatory treatment complications.

Key words:
positron emission tomography – germ cell tumour – diagnosis – therapy

With the support of the Czech Ministry of Health’s grant IGA NS 10420-3/2009.

The authors declare they have no potential conflicts of interest concerning drugs, products, or services used in the study.

The Editorial Board declares that the manuscript met the ICMJE “uniform requirements” for biomedical papers.

Submitted:
2. 6. 2011

Accepted:
18. 8. 2011

Zdroje

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