Impact of Treatments to Improve Cognitive Function and Quality of Life on Cancer Patients with Carcinoma of the Testes
Authors:
L. Vasiľková
Authors place of work:
Psychologická ambulancia, Poliklinika, Národný onkologický ústav, Bratislava, Slovenská republika
Published in the journal:
Klin Onkol 2016; 29(4): 267-273
Category:
Review
doi:
https://doi.org/10.14735/amko2016267
Summary
Background:
Testicular cancer is one of the most common and most treatable cancers in men aged 15–49 years. The high survival rates mean that it is essential to maintain quality of life and minimize adverse effects associated with treatment. Both malignant tumors and the modalities used to treatment them can have adverse effects from both a psychosocial and a neurocognitive function perspective. Recently, attention has focused on the negative impact of the disease and its treatment on the brain and on cognitive function, which can result in a form of neurocognitive dysfunction known as „chemo brain“ or „chemo fog“. Both cancer itself and the modalities used to treat it are associated with neurotoxicity and cognitive deficit, which are manifest in key areas of cognitive function. These problems may adversely affect both patients undergoing treatment and those in remission, with a consequent reduction in quality of life. Because many patients survive testicular cancer, it is important to understand the characteristics, range, and time course of disease symptoms, treatment, and side effects, all of which can lead to long-term physical, psychological, and social problems. Testicular cancer has a high potential for cure; therefore, patients suffer not only short-term but also long-term side effects associated with therapy.
Aims:
This article aims to offer a complete and concise overview of cognitive dysfunction and quality of life for patients with testicular cancer.
Conclusion:
It would be beneficial if research into testicular cancer also focused on the relationships between psychosocial factors, psychological disorders, and cognitive function.
Key words:
cognitive functions – quality of life – sexuality – body image
The author declares she has no potential conflicts of interest concerning drugs, products, or services used in the study.
The Editorial Board declares that the manuscript met the ICMJE recommendation for biomedical papers.
Submitted:
1. 12. 2015
Accepted:
20. 3. 2016
Zdroje
1. Sokoloff MH, Joyce GF, Wise M et al. Testis cancer. J Urol 2007; 177(6): 2030– 2041.
2. Holzner B, Efficace F, Basso U et al. Cross-cultural development of an EORTC questionnaire to assess health-related quality of life in patients with testicular cancer: the EORTC QLQ-TC26. Qual Life Res 2013; 22(2): 369– 378. doi: 10.1007/ s11136-012-0147-1.
3. Jean-Pierre P, Johnson-Greene D, Burish TG. Neuropsychological care and rehabilitation of cancer patients with chemo brain: strategies for evaluation and intervention development. Support Care Cancer 2014; 22(8): 2251– 2260. doi: 10.1007/ s00520-014-2162-y.
4. Correa DD, Ahles TA. Neurocognitive changes in cancer survivors. Cancer J 2008; 14(6): 396– 400. doi: 10.1097/ PPO.0b013e31818d8769.
5. Ahles TA, Saykin AJ. Candidate mechanisms for chemotherapy-induced cognitive changes. Nat Rev Cancer 2007; 7(3): 192– 201.
6. Joly F, Rigal O, Noal S et al. Cognitive dysfunction and cancer: which consequences in terms of disease management? Psychooncology 2011; 20(12): 1251– 1258. doi: 10.1002/ pon.1903.
7. Hess LM, Insel KC. Chemotherapy-related change in cognitive function: a conceptual model. Oncol Nurs Forum 2007; 34(5): 981– 994.
8. Wefel J, Vidrine DJ, Veramonti TL et al. Cognitive impairment in men with testicular cancer prior to adjuvant therapy. Cancer 2011; 117(1): 190– 196. doi: 10.1002/ cncr.25298.
9. Schagen SB, Boogerd W, Muller MJ et al. Cognitive complaints and cognitive impairment following BEP chemotherapy in patients with testicular cancer. Acta Oncologica 2008; 47(1): 63– 70.
10. Hermelink K, Küchenhoff H, Untch M. Two different sides of ‘chemobrain’: determinants and nondeterminants of self-perceived cognitive dysfunction in a prospective, randomized, multicenter study. Psychooncology 2009; 19(12): 1321– 1328. doi: 10.1002/ pon.1695.
11. Kerestes R, Ladouceur CD, Meda S et al. Abnormal prefrontal activity subserving attentional control of emotion in remitted depressed patients during a working memory task with emotional distracters. Psychol Med 2011; 42(1): 29– 40. doi: 10.1017/ S0033291711001097.
12. Bird CM, Burgess N. The hippocampus and memory: insight from spatial processing. Nat Rev Neurosci 2008; 9(3): 182– 194. doi: 10.1038/ nrn2335.
13. Schiepers OJ, Wichers MC, Maes M. Cytokines and major depression. Prog Neuropsychopharmacol Biol Psychiatry 2005; 29(2): 201– 217.
14. de Raaf PJ, de Klerk C, van der Rijt CC et al. Elucidating the behavior of physical fatigue and mental fatigue in cancer patients: a review of the literature. Psychooncology 2013; 22(9): 1919– 1929. doi: 10.1002/ pon.3225.
15. Luckett T, King MT, Stockler MR. Quality of life research in prostate and testicular cancer. Cancer Forum 2010; 34(1): 20– 23.
16. Wall D, Kristjanson L. Men, culture and hegemonic masculinity: understanding the experience of prostate cancer. Nurs Inq 2008; 12(2): 87– 97.
17. Cecil R, Mc Caughan E, Parahoo K. It’s hard to take because I am a man’s man: an ethnographic exploration of cancer and masculinity. Eur J Cancer Care (Engl) 2010; 19(4): 501– 509. doi: 10.1111/ j.1365-2354.2009.01085.x.
18. Šrámková T. Poruchy sexuality u somaticky nemocných a jejich léčba. Praha: Grada 2013.
19. Alacacioglu A, Ulger E, Varol U et al. Sexual satisfaction, anxiety, depression and quality of life in testicular cancer survivors. Med Oncol 2014; 31(7): 31– 43. doi: 10.1007/ s12032-014-0043-3.
20. Rieker PP, Fitzgerald EM, Kalish LA. Adaptive behavioral responses to potential infertility among survivors of testis cancer. J Clin Oncol 1990; 8(2): 347– 355.
21. Ozen H, Sahin A, Toklu C et al. Psychosocial adjustment after testicular cancer treatment. J Urol 1998; 159(6): 1947– 1950.
22. Bumbasirevic U, Bojanic N, Pekmezovic T et al. Health-related quality of life, depression, and sexual function in testicular cancer survivors in a developing country: a Serbian experience. Support Care Cancer 2012; 21(3): 757– 763. doi: 10.1007/ s00520-012-1577-6.
23. Jones GY, Payne S. Searching for safety signals: the experience of medical surveillance among men with testicular teratomas. Psychooncology 2000; 9(5): 385– 394.
24. Stoehr B, Schachtner L, Pichler R et al. Influence of achieved paternity on quality of life in testicular cancer survivors. BJU Int 2013; 111(4): 207– 212. doi: 10.1111/ j.1464-410X.2012.11579.x.
25. Kim C, McGlynn KA, McCorkle R et al. Quality of life among testicular cancer survivors: a case-control study in the United States. Qual Life Res 2011; 20(10): 1629– 1637. doi: 10.1007/ s11136-011-9907-6.
Štítky
Paediatric clinical oncology Surgery Clinical oncologyČlánok vyšiel v časopise
Clinical Oncology
2016 Číslo 4
- Metamizole at a Glance and in Practice – Effective Non-Opioid Analgesic for All Ages
- Metamizole vs. Tramadol in Postoperative Analgesia
- Spasmolytic Effect of Metamizole
- Possibilities of Using Metamizole in the Treatment of Acute Primary Headaches
- Current Insights into the Antispasmodic and Analgesic Effects of Metamizole on the Gastrointestinal Tract
Najčítanejšie v tomto čísle
- The Influence of Palliative Chemotherapy on the Quality of Life of Patients with Gastric Cancer
- Two Approaches to Cancer Development
- Impact of Treatments to Improve Cognitive Function and Quality of Life on Cancer Patients with Carcinoma of the Testes
- Multiple Primary Lung Cancer – a Case Report and Literature Review