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How fatigue affects return to work in breast cancer patients


Authors: K. A. Černíková;  L. Klůzová Kráčmarová;  M. Pešoutová;  P. Tavel
Authors place of work: Institut sociálního zdraví, Cyrilometodějská teologická fakulta UP v Olomouci
Published in the journal: Klin Onkol 2022; 35(4): 290-296
Category: Original Articles
doi: https://doi.org/10.48095/ccko2022290

Summary

Background: Fatigue after breast cancer treatment affects one in four women. Feeling tired affects women‘s daily activities, coping with the disease and quality of life. After active treatment, women want to return to their working lives, where fatigue is a barrier. Despite the fact of fatigue being such a common consequence of the treatment, it seems to be often overlooked. Materials and methods: This article is a substudy of the research focused on the complex experience of women with breast cancer. In this substudy, we focus on breast cancer patients‘ perceptions of fatigue and its impact on daily life. A qualitative methodology was used to collect the data. The interviews were structured into two consecutive parts. The first, narrative part was followed by a semi-structured interview. The research population was recruited to meet the conditions of maximum variation sample (different regions of the country, age categories, education, stage of the disease, and treatment modality). Fifty-three interviews were collected and transcribed verbatim. The data from which the categories were created were analysed using NVivo10 software and were open coded. The codes were then grouped into themes for thematic analysis. Results: Most women experienced fatigue as a consequence of the disease. Fatigue often forced them to change their lifestyle. The women perceived great limitations when returning to work. They did not feel ready to return to work and often postponed it or considered changing their working hours or a type of job. Conclusion: Fatigue seems to be an underestimated consequence of the treatment in breast cancer patients. It often leads to a forced change in women‘s lifestyle, which has a negative impact on their mental health. Methods to monitor fatigue and early interventions are needed to improve women‘s quality of life after the treatment.


Zdroje

1. Abrahams HJG, Gielissen MFM, Schmits IC et al. Risk factors, prevalence, and course of severe fatigue after breast cancer treatment: a meta-analysis involving 12 327 breast cancer survivors. Ann Oncol 2016; 27 (6): 965–974. doi: 10.1093/annonc/mdw099.

2. Maass S, Brandenbarg D, Boerman LM et al. Fatigue among long-term breast cancer survivors: a controlled cross-sectional study. Cancers 2021; 13 (6): 1301. doi: 10.3390/cancers13061301.

3. Minton O, Berhall A, Barsevick A et al. Cancer-related fatigue and its impact on functioning. Cancer 2013; 119 (Suppl 11): 2124–2130. doi: 10.1002/cncr.28058.

4. Reinertsen KV, Cvancarova M, Loge JH et al. Predictors and course of chronic fatigue in long-term breast cancer survivors. J Cancer Surviv 2010; 4 (4): 405–414. doi: 10.1007/s11764-010-0145-7.

5. Hofman M, Ryan JL, Figueroa-Moseley CD et al. Cancer-related fatigue: the scale of the problem. Oncologist 2007; 12 (Suppl 1): 4–10. doi: 10.1634/theoncologist.12-S1-4.

6. Ruiz-Casado A, Alvarez-Bustos A, de Pedro CG et al. Cancer-related fatigue in breast cancer survivors: a review. Clin Breast Cancer 2021; 21 (1): 10–25. doi: 10.1016/j.clbc.2020.07.011.

7. Meeske K, Smith AW, Alfano CM et al. Fatigue in breast cancer survivors two to five years post dia­gnosis: a HEAL study report. Qual Life Res 2007; 16 (6): 947–960. doi: 10.1007/s11136-007-9215-3.

8. Galiano-Castillo N, Ariza-Garcia A, Cantarero-Villanueva I et al. Depressed mood in breast cancer survivors: associations with physical activity, cancer-related fatigue, quality of life, and fitness level. Eur J Oncol Nurs 2014; 18 (2): 206–210. doi: 10.1016/j.ejon.2013.10.008.

9. Noal S, Levy C, Hardouin A et al. One-year longitudinal study of fatigue, cognitive functions, and quality of life after adjuvant radiotherapy for breast cancer. Int J Radiat Oncol Biol Phys 2011; 81 (3): 795–803. doi: 10.1016/j.ijrobp.2010.06.037.

10. Bower JE, Ganz PA, Irwin MR et al. Do all patients with cancer experience fatigue? A longitudinal study of fatigue trajectories in women with breast cancer. Cancer 2021; 127 (8): 1334–1344. doi: 10.1002/cncr.33327.

11. Schmidt ME, Chang-Claude J, Seibold P et al. Determinants of long-term fatigue in breast cancer survivors: results of a prospective patient cohort study. Psychooncology 2015; 24 (1): 40–46. doi: 10.1002/pon.3581.

12. Servaes P, Verhagen C, Bleijenberg G. Fatigue in cancer patients during and after treatment: prevalence, correlates and interventions. Eur J Cancer 2002; 38 (1): 27–43. doi: 10.1016/s0959-8049 (01) 00332-x.

13. Álvarez-Bustos A, de Pedro CG, Romero-Elías M et al. Prevalence and correlates of cancer-related fatigue in breast cancer survivors. Support Care Cancer 2021; 29 (11): 6523–6534. doi: 10.1007/s00520-021-06218-5.

14. Alexander S, Minton O, Andrews P et al. A comparison of the characteristics of disease-free breast cancer survivors with or without cancer-related fatigue syndrome. Eur J Cancer 2009; 45 (3): 384–392. doi: 10.1016/j.ejca.2008.09.010.

15. Goedendorp MM, Gielissen MFM, Verhagen C et al. Development of fatigue in cancer survivors: a prospective follow-up study from dia­gnosis into the year after treatment. J Pain Symptom Manage 2013; 45 (2): 213–222. doi: 10.1016/j.jpainsymman.2012.02.009.

16. Bower JE, Ganz PA, Desmond KA et al. Fatigue in long-term breast carcinoma survivors – a longitudinal investigation. Cancer 2006; 106 (4): 751–758. doi: 10.1002/cncr.21671.

17. Fabi A, Falcicchio C, Giannarelli D et al. The course of cancer related fatigue up to ten years in early breast cancer patients: what impact in clinical practice? Breast 2017; 34: 44–52. doi: 10.1016/j.breast.2017.04.012.

18. Kowalczyk L, Deutschmann C, Crevenna R et al. Radiotherapy-induced fatigue in breast cancer patients. Breast Care 2021; 16 (3): 236–242. doi: 10.1159/000509410.

19. Servaes P, Gielissen MFM, Verhagen S et al. The course of severe fatigue in disease-free breast cancer patients: a longitudinal study. Psychooncology 2007; 16 (9): 787–795. doi: 10.1002/pon.1120.

20. Bodtcher H, Bidstrup PE, Andersen I et al. Fatigue trajectories during the first 8 months after breast cancer dia­gnosis. Qual Life Res 2015; 24 (11): 2671–2679. doi: 10.1007/s11136-015-1000-0.

21. Schmidt ME, Chang-Claude J, Vrieling A et al. Fatigue and quality of life in breast cancer survivors: temporal courses and long-term pattern. J Cancer Surviv 2012; 6 (1): 11–19. doi: 10.1007/s11764-011-0197-3.

22. Abrahams HJG, Smits L, De Lugt M et al. Severe fatigue after treatment of ductal carcinoma in situ: a comparison with age-matched breast cancer survivors and healthy controls. Breast 2017; 31: 76–81. doi: 10.1016/ j.breast.2016.10.020.

23. Kluthcovsky A, Urbanetz AA. Fatigue and quality of life in breast cancer survivors: a comparative study. Rev Bras Ginecol Obstet 2015; 37 (3): 119–126. doi: 10.1590/so100-720320150005247.

24. Hall DL, Mishel MH, Germino BB. Living with cancer-related uncertainty: associations with fatigue, insomnia, and affect in younger breast cancer survivors. Support Care Cancer 2014; 22 (9): 2489–2495. doi: 10.1007/s00520-014-2243-y.

25. Porro B, Michel A, Zinzindohoue C et al. Quality of life, fatigue and changes therein as predictors of return to work during breast cancer treatment. Scand J Caring Sci 2019; 33 (2): 467–477. doi: 10.1111/scs.12646.

26. Munir F, Kalawsky K, Lawrence C et al. Cognitive intervention for breast cancer patients undergoing adjuvant chemotherapy a needs analysis. Cancer Nurs 2011; 34 (5): 385–392. doi: 10.1097/NCC.0b013e3182025 4f3.

27. Dorland HF, Abma FI, Roelen CAM et al. Work-specific cognitive symptoms and the role of work characteristics, fatigue, and depressive symptoms in cancer patients during 18 months post return to work. Psychooncology 2018; 27 (9): 2229–2236. doi: 10.1002/pon.4800.

28. Schmidt ME, Scherer S, Wiskemann J et al. Return to work after breast cancer: the role of treatment-related side effects and potential impact on quality of life. Eur J Cancer Care 2019; 28 (4): e13051. doi: 10.1111/ecc.13051.

29. Duijts SFA, van Egmond MP, Spelten E et al. Physical and psychosocial problems in cancer survivors beyond return to work: a systematic review. Psychooncology 2014; 23 (5): 481–492. doi: 10.1002/pon.3467.

30. Vrtělová P, Coufal O, Fait V et al. Lymphoedema following regional lymph node surgery for breast cancer. Klin Onkol 2017; 30 (1): 34–40. doi: 10.14735/amko201734.

31. Carlsen K, Jensen AJ, Rugulies R et al. Self-reported work ability in long-term breast cancer survivors. A population-based questionnaire study in Denmark. Acta Oncol 2013; 52 (2): 423–429. doi: 10.3109/0284186x.2012.744877.

32. Ruggieri R, Gahanelli P, Belluccio C et al. Return to work after breast cancer: barriers and facilitators. Giornale Italiano Di Medicina Del Lavoro Ed Ergonomia 2021; 43 (1): 66–73.

33. Goldstein D, Bennett BK, Webber K et al. Cancer-related fatigue in women with breast cancer: outcomes of a 5-year prospective cohort study. J Clin Oncol 2012; 30 (15): 1805–1812. doi: 10.1200/jco.2011.34.6148.

34. Minton O, Alexander S, Stone PC. Identification of factors associated with cancer related fatigue syndrome in disease-free breast cancer patients after completing primary treatment. Breast Cancer Res Treat 2012; 136 (2): 513–520. doi: 10.1007/s10549-012-2284-1.

35. Kim SH, Son BH, Hwang SY et al. Fatigue and depression in disease-free breast cancer survivors: prevalence, correlates, and association with quality of life. J Pain Symptom Manage 2008; 35 (6): 644–655. doi: 10.1016/j.jpainsymman.2007.08.012.

36. Kluthcovsky A, Urbanetz AA, de Carvalho DS et al. Fatigue after treatment in breast cancer survivors: prevalence, determinants and impact on health-related quality of life. Support Care Cancer 2012; 20 (8): 1901–1909. doi: 10.1007/s00520-011-1293-7.

37. Andrykowski MA, Donovan KA, Laronga C et al. Prevalence, predictors, and characteristics of off-treatment fatigue in breast cancer survivors. Cancer 2010; 116 (24): 5740–5748. doi: 10.1002/cncr.25294.

38. Horneber M, Fischer I, Dimeo F et al. Cancer-related fatigue epidemiology, pathogenesis, dia­gnosis, and treatment. Dtsch Arztebl Int 2012; 109 (9): 161–171. doi: 10.3238/arztebl.2012.0161.

39. Berger AM, Mitchell SA, Jacobsen PB et al. Screening, evaluation, and management of cancer-related fatigue: ready for implementation to practice? CA Cancer J Clin 2015; 65 (3): 190–211. doi: 10.3322/caac.21 268.

40. Pearson EJM, Morris ME, McKinstry CE. Cancer related fatigue: implementing guidelines for optimal management. BMC Health Serv Res 2017; 17 (1): 496. doi: 10.1186/s12913-017-2415-9.

41. Ziebland S, McPherson A. Making sense of qualitative data analysis: an introduction with illustrations from DIPEx (personal experiences of health and illness). Med Educ 2006; 40 (5): 405–414. doi: 10.1111/j.1365-2929.2006.02467.x.

42. Tavel P, Klůzová Kráčmarová L, Půžová Z et al. Metodika DIPEx ČR. Certifikovaná metodika MPSV č.j.: 2015/70065-312. Olomouc: Institut sociálního zdraví na Univerzitě Palackého 2015.

Štítky
Paediatric clinical oncology Surgery Clinical oncology

Článok vyšiel v časopise

Clinical Oncology

Číslo 4

2022 Číslo 4
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