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Basalioma of the Eyelid: Rate and Factors of Recurrence after Surgical Therapy


Authors: Z. Svetlošáková;  M. Halás;  V. Krásnik;  P. Strmeň
Authors place of work: Klinika oftalmológie LFUK a UNB, Bratislava, prednosta prof. MUDr. Peter Strmeň, CSc.
Published in the journal: Čes. a slov. Oftal., 66, 2010, No. 4, p. 171-175
Category: Original Article

Summary

The aim of our study
was to evaluate a recurrence rate of basalioma of the eyelid after surgical therapy. In our cohort of patients we also assessed a relation between the recurrence and chosen clinical parameters (localisation and size of tumour, TNM classification, histopathological grade of differentiation, margins of excision).

Material and methods:
Retrospective analysis of data from patients with basalioma of the eyelid treated surgically at the Department of Ophthalmology, Faculty of Medicine Comenius University in Bratislava during the years 2005–2007. The excision exceeded the macroscopically visible margins of tumor with a safety margin of 2–3 mm into the healthy tissue.

Results:
In our cohort we studied 67 histologically proven tumors in 65 patients. During a mean follow-up time of 24.6 ± 13.6 months we found a recurrence in 4 tumors (6,0%), one of them subsequently recidivated for a second time. There was no statistically significant relation between the studied parameters and a tumor recurrence.

Conclusion:
Our recurrence rate of 6.0% is comparable with the published results from other centers.

Key words:
basalioma of the eyelid, surgical therapy, factors of recurrence


Zdroje

1. Allali, J., D`Hermes, F., Renard, G.: Basal Cell Carcinoma of the Eyelids. Ophthalmologica, 219, 2005, 2: 57–71.

2. Bednář, B., Dobiáš, J., Motlík, K. et al.: Základy klasifikace nádorů a ejich léčení, Praha, AVICENUM, 1987, 1–737p.

3. Carter, KD., Nerad, JA., Whitaker, DC.: Clinical factors influencing periocular surgical defects after Mohs micrographic surgery. Ophthal Plast Reconstr Surg, 15, 1999, 2: 83–91.

4. Ducasse, A., Pluot, M., Gotzamanis, A.: Factors of recurrence of basal cell carcinomas of the eyelid, J Fr Ophtalmol. 25, 2002, 5: 512–516.

5. Font, RL., Croxatto, JO., Rao, NA.: Tumors of the eye and ocular adnexa, Washington, American Registry of Pathology, 2006, 1–339 p.

6. Furdová, A., Kelečínová, Z.: Bazalióm mihalníc a rbity. Multimediálna podpora výučby klinických a dravotníckych odborov, Portál Lekárskej fakulty Univerzity Komenského v Bratislave [online] 3.3.2009, posledná aktualizácia 6.5.2009 [cit.2010-03-16], dostupný z www: <http://portal.fmed.uniba.sk/ clanky.php?aid=15>. ISSN 1337-9577.

7. Furdová, A., Macák, D., Poruban, Š.: Karcinóm mihalnice vychádzajúci z eibomovej žľazy. Čes. a lov. Oftal., 59, 2003, 1: 119–126.

8. Furdová, A., Strmeň, P., Oláh, Z.: Použitie TNM klasifikácie v ftalmológii. Choroby hlavy a rku. Head and Neck Diseases, 9, 2000, 2: 17–25.

9. Furdová, A., Svetlošáková, Z.: Bazaliómy v blasti oka a ihalníc. Dermatológia pre prax, 3, 2009, 3: 115–117.

10. Kaušitz, J., Altaner, Č. (Eds.): Onkológia. Bratislava, VEDA, 2003, 1–712 p.

11. Nemet, AY., Deckel, Y., Martin, PA.: Management of periocular basal and squamous cell carcinoma: a series of 485 cases. Am J Ophthalmol, 142, 2006, 2: 293–297.

12. Ondrušová, M., Pleško, I., Safaei-Diba, Ch. et al: Komplexná analýza výskytu a úmrtnosti na zhubné nádory v Slovenskej republike [online]. Bratislava, Národný onkologický register SR, NCZI, 2007 [cit. 14.2.2010]. http://www.nor-sk.org/. ISBN 978-80-89292-05-9.

13. Paavilainen, V., Tuominen, J., Aho, VV.: Long-term results after treatment of basal cell carcinoma of the eyelid in South-Western Finland. Eur J Ophthalmol, 17, 2007, 4: 494–500.

14. Paavilainen, V., Tuominen, J., Pukkala, E., Saari, KM.: Basal cell carcinoma of the eyelid in Finland during 1953–97. Acta Ophthalmol Scand, 83, 2005, 2: 215–20.

15. Rowe, DE., Carroll, RJ., Day, CL.: Long term recurrence rates in previously treated basal cell carcinoma: Implications for patient follow-up. J Dermatol Surg Oncol, 15, 1989, 3: 315–328.

16. Seongmu, L., Dinesh, S., Shyamala, C. et al.: Pharmacological Treatments for Basal Cell Carcinoma. Drugs, 67, 2007, 6: 915–934.

17. Sigurdsson, H., Agnarsson, BA.: Basal cell carcinoma of the eyelid, Risk of recurrence according to adequacy of surgical margins. Acta Ophthalmol Scand, 76, 1998, 4: 477–480.

18. Wong, VA., Marshall, JA., Whitehead, KJ.: Management of periocular basal cell carcinoma with modified en face frozen section controlled excision. Ophthal Plast Reconstr Surg, 18, 2002, 6: 430–435.

19. Xu, XL., Li, B., Sun, XL. et al.: Eyelid Neoplasms in the Beijing Tongren Eye Centre Between 1997 and 2006. Ophthalmic Surg Lasers Imaging, 39, 2008, 5: 367–372.

Štítky
Ophthalmology
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