BILATERAL AMYLOIDOSIS OF THREE EYELIDS. A CASE REPORT
Authors:
J. Krásný 1; J. Šach 2; H. Hůlková 3; P. Pavlíček 4
Authors place of work:
Oční klinika FN Královské Vinohrady, Praha
1; Ústav patologie FN Královské Vinohrady, Praha
2; Ústav patologie Všeobecná FN, Praha
3; Hematologická klinika FN Královské Vinohrady, Praha
4
Published in the journal:
Čes. a slov. Oftal., 77, 2021, No. 5, p. 257-263
Category:
Case Report
doi:
https://doi.org/10.31348/2021/29
Summary
Aim: To present rare form of lids amyloidosis, in the context with literature and remind a Czech professor Vrabec, F., MD, an important pan-European ocular histologist.
Case report: 37 years aged man was examined for eyelids mass on the department of ophthalmology of the Teaching Hospital Kralovske Vinohrady, Prague, Czech Republic in June 2018. The finding looked like chronic chalazion on the right side and chronic hordeolum on the left side. No acute phase was noted within last several months by the patient. Yellowish to lightly brown friable, partially transparent mass was obtained by excision. Amyloidosis of the AL type was revealed histologically, and diagnosis was followed by extended excision and plastic surgical reconstruction of the lower eyelids on both sides. No systemic disease underlying the amyloidosis was disclosed by following through diagnostic work-up of the patient.
Results: Amyloidosis was illustrated initially by Congo red staining with characteristic dichroism in the polarized light, then it was analysed immunohistochemically, with positivity for kappa light chains. Systemic amyloidosis was excluded, as well as monoclonal gamapathy. Only slightly increased number of plasmacytes (up to 10 %) was revealed in the bone marrow biopsy. The surgical solution was optimal for the patient, and he was without any recurrence and problems of lower eyelids three years.
Conclusion: Described case of bilateral eyelids amyloidosis without underlying systemic disease belongs to rare cases and also illustrates necessity of complex interdisciplinary cooperation in the diagnostic process.
Keywords:
ocular amyloidosis – palpebral mass – plastic surgery of conjunctiva
Zdroje
1. Duke-Elder S. System of Ophthalmogy, 1st ed. London (Great Britain): H. Kimpton; 1963. Volume XIII, The ocular adnexa; 13-318.
2. Sedláček J. Prof. MUDr. František Vrabec, 65 let [prof. Vrabec Frantisek, MD, 65 years]. Cesk Oftalmol. 1976;22(6):475-476. Czech.
3. Krásný J, Dušek J, Vrabec F. Oční projevy při oxalóze [Ocular manifestations in oxalosis]. Cesk Oftalmol. 1985;41(4):258-262. Czech.
4. Kuchynka P, Vrabec F, Krásný J, Křepelková J. Vrozený defekt čočky u syndromu Pierre-Robina [Congenital defekt lenses in Pierre-Robin] Cesk Oftalmol. 1985;41(6):62-65. Czech.
5. Gertz MA, Rajmukar VS. Amyloidosis: Diagnosis and Treatment. Boston (USA); Spriger Science and Businnes Medica; 2010. 238.
6. Ryšavá R. Systémové amyloidózy a jejich léčba [Systemic amyloidosis and their treatment] Praha (Czech Republic): Maxdorf; 2013. 135. Czech.
7. Knowles DM 2nd, Jakobiec FA, Rosen M, Howard G. Amyloidosis of the orbit and adnexae. Surv Ophthalmol. 1975;19(6):376-384.
8. Mora-Horna ER, Rojas-Padilla R, López VG, Guzmán MJ, Ceriotto A, Salcedo G. Ocular adnexal and orbital amyloidosis: a case series and literature review. Int Ophthalmol. 2016;36(2):281-291.
9. Leibovitch I, Selva D, Godberg RA, et al. Periocular and orbital amyloidosis: clinical characteristics management, and outcome. Ophthalmology. 2006;113(9):1657-1664.
10. Medel JR, Sánchez-Espaňa JC, Vasquez LM, et al. Orbital and peri- -orbital amyloidosis: A report of four cases. Orbit. 2018 Mar;22:1-6. doi:10.1080/01676830.2018.1449868
11. Tyradellis C, Peponis V, Kulwin D. Surgical management of recurrent localized eyelid amyloidosis. Ophthalmic Plast Reconstr Surg. 2006;22(4):308-309.
12. Di Bari R, Guerriero S, Giancipoli G, Cantore A, Sborgia G, Piscitelli D. Primary localized orbital amyloidosis: a case report. Eur J Ophthalmol. 2006;16(6):895-897.
13. Reynolds MM, Veverka KK, Gertz MA, et al. Ocular manifestations of systematic amyloidosis. Retina. 2018;38(7):1371-1376.
14. Shah VS, Cavuoto KM, Capo H, Grace SF, Dubovy SR, Schatz NJ. Systemic amyloidosis and extraocular musle deposition. J Neuroophthalmol. 2016;36(2):167-173.
15. Krásný J, Šach J, Zikmund J. Merkel´s eyelid carcinoma – clinical histological study Cesk Slov Oftal. 2018;74(5):198-205. doi:10.31348/2018/5/5
16. Naxer S, Behnes CL, Schitkowski MP. Amyloidosis. A rare differential diagnosis of an orbital tumor. Klin Monbl Augenheilkd. 2011;228(6):554-564.
17. Meduri A, Rechichi M, Mazzotta C, Scalinci SZ, Jaroudi MO. Ectropium and conjunctival mass a patient primary bilateral conjuctival amyloidosis. Case Rep Ophthalmol Med. 2016 Nov; 2016:5610753.
18. Demirci H, Shields CL, Eagle RC Jr, Shields JA. Conjuctival amyloidosis: report of six cases and review of the literature. Surv Ophthalmol. 2006;51(4):419-433.
19. Spitellie PH, Jordan DR, Gool P. Primary localized conjunctival amyloidosis simulating a lymphoproliferative disorder. Ophthal Plast Reconstr Surg. 2008;24(5):417-419.
20. Prager AJ, Habib AL, Gambogi T, Busam KJ, Marr BP. Long-term follow- up of 4 patients with conjuctival amyloidosis. Ocular Oncol Path. 2018;4:313-317. doi.orig/10.1159/000485918918
21. Correa LJ, Maccio JP, Esposito E, et al. Systematic amyloidosis with bilateral conjunctival involvement: a case report. BMC Ophthalmol. 2015 Jul 19;15:77. doi:10.1186/s12886-015-0075-2
22. Pirouzmand F, Hurwitz J, Howarth, D. Primary localized bilateral conjunctival amyloidosis and epiphora. Orbit. 2002;21(2):139-144.
23. Chakraborti C, Chaudhury KP, Biwas RR. Primary conjunctival amyloidosis. Oman J Ophthalmol. 2014;7(1):16-18.
24. Shields JA, Eagle RC, Shields CL, Green M, Singh AD. Systemic amyloidosis presenting as a mass of the conjuctival semilunar fold. Am J Ophthalmol. 2000;130(4):523-525.
25. Scuderi G, Abdolrahimzadeh S, Troccola A, Mazzocchi M, Recupero SM. Surgical treatment of a rare case of bilateral ptosis due to localized ocular amyloidosis. Saudi J Ophthalmol. 2016;30(3):201-203.
26. Garcia de Oteyza G, Ede la Paz M, Charoenrook de la Funte V. Unilateral tarzal amyloidosis. Arch Soc Esp Oftalmol. 2016;91(11):556- 558.
27. Kamal S, Goel R, Bodh SA. Primary localized amyloidosis presentig as a tarzal mass: report of two cases. Middle East Afr J Ophthalmol. 2012;19(4):426-428.
28. Nelson GA, Edward DP, Wilensky JT. Ocular amyloidosis and secondary glaucoma. Ophthalmology. 1999;106(7):1363-1366.
29. Venkatesh P, Selvan H, Singh SB, et al. Vitreous amyloidosis: ocular systemic and genetic insights. Ophthalmology. 2017;124(7):1014- 1022.
Štítky
OphthalmologyČlánok vyšiel v časopise
Czech and Slovak Ophthalmology
2021 Číslo 5
Najčítanejšie v tomto čísle
- ARTEFICIAL INTELLIGENCE IN DIABETIC RETINOPATHY SCREENING. A REVIEW
- BILATERAL AMYLOIDOSIS OF THREE EYELIDS. A CASE REPORT
- SHORT-WAVELENGTH AUTOMATED PERIMETRY IN DIABETIC PATIENTS WITHOUT RETINOPATHY
- Prof. MUDr. Anton Gerinec, CSc. – ENCYKLOPÉDIA OFTALMOLÓGIE