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Iridocorneal Endothealial Syndrome. Case Reports

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Iridokorneální endotelový syndrom. Kazuistiky

Úvod: Iridokorneální endotelový (ICE) syndrom je vzácné onemocnění charakterizované abnormální proliferací a strukturálními změnami endotelu, obliterací iridokorneálního úhlu a anomáliemi duhovky. Důsledkem těchto změn je sekundární glaukom a dekompenzace rohovky. Etiologie je nejasná a častěji postihuje ženy středního věku.

Kazuistiky: Formou článku prezentujeme dvě odlišné kazuistiky mladých pacientů s diagnózou ICE syndromu s rozvinutými komplikacemi. V 1. kazuistice se jedná o mladou pacientku, u které se pomocí antiglaukomové a rohovkové chirurgie daří stabilizovat glaukomové onemocnění a rohovkový edém. Naproti tomu kazuistika 2. poukazuje na složitý a komplikovaný případ 29letého pacienta, u kterého ani přes opakované zákroky není léčba úspěšná.

Závěr: Tento text poukazuje na komplikovanost ICE syndromu, obtížnost jeho terapie a důležitost včasné diagnostiky.

Klíčová slova:

sekundární glaukom – iridokorneální endotelový syndrom – onemocnění rohovky

Authors: Kristýna Lahodová;  Zuzana Hlinomazová;  Klára Samková;  Magdalena Vokrojová
Authors place of work: Oční klinika Lexum Praha
Published in the journal: Čes. a slov. Oftal., 80, 2024, No. 4, p. 1-7
Category: Case Report
doi: https://doi.org/10.31348/2024/27

Summary

Aim: Iridocorneal endothelial (ICE) syndrome is a rare disease characterized by abnormal proliferation and structural changes of the endothelium,

obliteration of the iridocorneal angle, and anomalies of the iris. The consequence of these changes is secondary glaucoma and corneal decompensation. The etiology is unclear, and the syndrome more commonly affects middle-aged women.

Case reports: In this article we present two different case studies of young patients diagnosed with ICE syndrome with complications. The first case report is about a young woman in whom surgical treatment of glaucoma and corneal edema was successful. On the other hand, the second report presents a complicated case of a 29-year-old patient whose treatment was not successful despite repeated interventions.

Conclusion: This text highlights the complexity of ICE syndrome, the difficulty of its therapy and the importance of early diagnosis.

Keywords:

secondary glaucoma – iridocorneal endothelial syndrome – corneal diseases

Zdroje
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Czech and Slovak Ophthalmology

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