Jsou některé vakcíny COVID-19 lepší než jiné, pokud jde o krátkodobé nežádoucí účinky?
Autori:
Radhwan Al-Zidan; Omeed Darweesh; Muhanad Salah; Pshtiwan Bebane; Hemn Ahmed; Ghayth Abdulrazzaq; Sadeel Shanshal; Nohad Alomari
Vyšlo v časopise:
Čes. slov. Farm., 2023; 72, 45-54
Kategória:
Original Article
doi:
https://doi.org/https://doi.org/10.5817/CSF2023-1-45
Súhrn
Zvládnutí pandemie se dosahuje především očkováním proti COVID-19. Ačkoliv se ve světě používají různé vakcíny proti COVID-19, o jejich bezpečnosti a vedlejších účincích je známo jen málo. Cílem tohoto výzkumu je proto zjistit krátkodobé vedlejší účinky různých vakcín proti COVID-19 používaných v Iráku. Dále bylo cílem prozkoumat souvislost mezi pociťovanými nežádoucími účinky a značkou podané vakcíny. Současná studie hodnotila krátkodobé vedlejší účinky vakcín Pfizer, Sinopharm a AstraZeneca u pracovníků ve zdravotnictví v Iráku. Ve studii byl použit dotazník, který se skládal ze speciálních částí pro sběr demografických údajů, značky obdržené vakcíny covid-19, krátkodobých nežádoucích účinků a ochoty obdržet třetí posilovací dávku. Pokud jde o vedlejší účinky po očkování, studované vakcíny COVID-19 vykazovaly srovnatelnou škálu vedlejších účinků, jako jsou bolesti hlavy, horečka, bolesti svalů, bolesti kloubů, malátnost, citlivost, zarudnutí a také bolest v místě očkování. Vakcína Pfizer však vykazovala vyšší výskyt bolesti a citlivosti v místě vpichu a horečky ve srovnání s vakcínami AstraZeneca a Sinopharm. Na druhou stranu vakcína Sinopharm byla ve srovnání s vakcínami Pfizer a AstraZeneca spojena s vyšším výskytem bolestí hlavy, svalů, kloubů a malátnosti. Souhrnně lze říci, že krátkodobé nežádoucí účinky všech tří vakcín byly srovnatelné, nicméně vakcína AstraZeneca byla spojena s nižším rizikem výskytu nežádoucích účinků.
Klíčová slova:
nežádoucí účinky – COVID-19 – vakcína – Pfizer – Sinopharm – AstraZeneca – Sputnik V
Zdroje
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Štítky
Pharmacy Clinical pharmacologyČlánok vyšiel v časopise
Czech and Slovak Pharmacy
2023 Číslo 1
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