Dissociation and Cognitive Function in Obsessive-compulsive Disorder – cross-sectional study
Authors:
M. Raszka; J. Praško; K. Adamcová; J. Kopřivová; J. Vyskočilová
Authors place of work:
Psychiatrické centrum Praha
ředitel prof. MUDr. C. Höschl, DrSc., FRCPsych.
Published in the journal:
Čes. a slov. Psychiat., 104, 2008, No. 6, pp. 289-296.
Category:
Original Article
Summary
According to recent findings, clinical symptoms in patients with obsessive-compulsive disorder (OCD) may be related to dissociation and impaired attentional processes. The aim of the present study was to evaluate relations between measures of dissociation, attention and psychopathology in obsessive-compulsive disorder.
Methods:
The study sample comprised of 33 patients with OCD (18 female). Obsessive-compulsive symptoms, anxiety and depression were assessed by objective and subjective rating scales. Dissociation was quantified by the Dissociative Experiences Scale (DES) and the Somatoform Dissociation Questionnaire-20 (SDQ-20). Attention, cognitive and behavioral inhibition was evaluated by the Stroop Color and Word Test and the Continuous Performance Test (CPT-II).
Results:
Positive correlation was found between obsessive-compulsive symptoms as assessed by the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS) and dissociation examined by DES and SDQ-20. Y-BOCS score correlated positively with severity of anxiety and depression. The level of dissociation assessed by both, DES and SDQ-20, correlated positively with anxiety and depression. Patients with OCD made less omission errors in comparison with normative data on the CPT. Between OCD patients and normative population samples there were no differences in interference time on the Stroop task, frequency of mistakes and reaction time on the CPT. No significant relationship was found between the neuropsychological assessments and dissociation.
Conclusion:
Our results suggest a possible relationship between dissociative symptoms and severity of obsessions and compulsions. However, the question remains to determine whether and to what it may be mediated by anxiety and depressive symptoms.
Key words:
obsessive-compulsive disorder, dissociation, cognitive function.
Zdroje
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