Hematologic malignancies in pregnancy

Česká verzia

Authors: R. Doubek ¹; D. Petrovová ¹; J. Kalvodová ¹; M. Doubek ²
Authors place of work: Gynekologicko-porodnická klinika LF MU a FN, Brno, přednosta prof. MUDr. P. Ventruba, DrSc. ¹; Interní hematoonkologická klinika LF MU a FN, Brno, přednosta prof. MUDr. J. Vorlíček, CSc. ²
Published in the journal: Ceska Gynekol 2009; 74(2): 138-143
Category: Original Article

Summary

Objective:
To summarize available data concerning hematologic malignancies in pregnancy.

Desine:
Review article.

Setting:
Department of Obstetrics and Gynekology, Fakulty of Medicine, Masaryk University and University Hospital Brno.

Methods:
Compilation of published data from scientific literature.

Conclusions:
Cancer complicating pregnancy is a rare coexistence. The incidence is approximately 1 in 1,000 pregnancies. The most frequent hematologic malignant tumor is Hodgkin’s lymphoma, leukemia is less frequent and myeloproliferative diseases complicating pregnancy are sporadic coexistence. Symptoms of these deseases are often nonspecific and disguised in pregnancy, then the diagnosis can be late. It is imperative that a multidisciplinary team involving hematooncologist and obstetrician (pediatric specialist) care for patient with hematologic malignancies. Cleary, every patient have to know whole prognosis and all risk factors of treatment. Optimum timing of delivery is after 36th week of pregnancy (when chemotherapy is ended more than two weeks ago). We prefer vaginal delivery to caesarean section.

Key words:
leukemia, lymphoma, myeloproliferative diseases, pregnancy, treatment.

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