Asherman’s syndrome I – history, prevalence, histopathology, classification, ethiology, symtomatology and investigations

Česká verzia

Authors: L. Hrazdírová; D. Kužel; Z. Žižka
Authors place of work: Gynekologicko-porodnická klinika VFN a 1. LF UK, Praha, přednosta prof. MUDr. A. Martan, DrSc.
Published in the journal: Ceska Gynekol 2010; 75(6): 492-498

Summary

Objective:
To describe the current knowledge of Ashermanęs syndrome – its history, prevalence, histopathology, classification, ethiology, symtomatology and investigations.

Design:
Review article.

Results:
There is presented the history of definition of Asherman’s syndrome. The origin of Asherman’s syndrome is in a fibrotisation of endometrium – the ethiologic factors are: an intrauterine trauma in connection with pregnancy, the trauma on nongravid uterus is in minority. There is not certificated that the inflammation without trauma can cause Asherman’s syndrome, exception the cases with genital TBC and schistosomiasis. The prevalence of Asherman’s syndrome depends on various factors: number of therapeutic and illegal abortions, on incidence of genital inflammation and TBC, on criteria used for diagnosis of IUA and etc. The typical symptomatology of this syndrome consisted of: menstrual abnormalities (hypomenorrhea, amenorrhoea), infertility, repeated pregnancy loss and pregnancy complications.

There were described a lot of classifications developed in relation with chosen diagnostic method. The gold standard in diagnosis and therapy is the hysteroscopy, the sonohysterography is very promissing diagnostic method.

Conclusion:
The Asherman’s syndrome is very complicated and severe disease that can significantly influence a possibility of woman conceive and give birth to a healthy child.

Key words:
intrauterine adhesion, Asherman’s syndrome, hysteroscopic adhesiolysis, infertility, hysteroscopy, amenorrhea.

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