Disorders of the thyroid gland in pregnancy

Česká verzia

Authors: A. Skřivánek ¹; M. Lubušký ^2,3; M. Studničková ² ; I. Holusková ⁴; M. Procházka ²
Authors place of work: G-Centrum Olomouc, vedoucí MUDr. A. Skřivánek ¹; Porodnicko-gynekologická klinika FN a LF UP, Olomouc, přednosta prof. MUDr. R. Pilka, Ph. D. ²; Ústav lékařské genetiky a fetální medicíny FN a LF UP, Olomouc, přednosta prof. MUDr. J. Šantavý, CSc. ³; Transfuzní oddělení FN a LF UP, Olomouc, primářka MUDr. D. Galuszková, MBA, Ph. D. ⁴
Published in the journal: Ceska Gynekol 2013; 78(1): 99-106

Summary

Functional disorder of the thyroid gland affects individuals of all ages. Incidence and nature of the disease is influenced by supplying iodine, genetic and immunological factors and other external effects. Increased function occurs in 1–2% of the adult population, reduced function in the younger population diagnosed in about 5%, in women aged over 50 years we have beenat 10–15%. The incidence of thyroid diseases is higher in women than in men (5–8:1) and significantly increases with age. Approximately as common as overt forms of thyroid disease are their subclinical forms. Thyroid disease, especially asymptomatic reduction of function for direct examination is diagnosed up to 5% of pregnant women. Untreated decreased thyroid function of mothers may have significant negative impact on the course of pregnancy, as well as on fetal development, especially in the psychomotoric area. Women with the presence of antithyroid antibodies are at risk of pregnancy deepening malfunctions and/or postpartum thyroiditis. Czech Endocrinological Society currently pursuing a systematic screening of other risk population groups, including notably the pregnant and nursing women, women in old age and ill with some other disease or treatment with certain drugs.

Keywords:
hypothyroidism – pregnancy – thyrotropin – free thyroxine – triiodothyronine – antithyroidantibodies

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