Can be considered the primary fallopian tube cancer an enigma at the beginning of the third millenium?

Česká verzia

Authors: J. Špaček ¹; J. Laco ²; J. Petera ³; I. Sedláková ¹; A. Řezáč ¹
Authors place of work: Porodnická a gynekologická klinika LF UK a FN, Hradec Králové, přednosta doc. MUDr. J. Špaček, Ph. D., IFEPAG ¹; Fingerlandův ústav patologie LF UK a FN, Hradec Králové, přednosta prof. MUDr. A. Ryška, Ph. D. ²; Klinika onkologie a radioterapie LF UK a FN, Hradec Králové, přednosta prof. MUDr. J. Petera, Ph. D. ³
Published in the journal: Ceska Gynekol 2013; 78(6): 501-508
Category: Original Article

Summary

Objective:
To analyze differences between primary fallopian tube cancer and ovarian cancer.

Design:
Overview study.

Setting:
Department of Obstetrics and Gynecology, The Fingerland Department of Pathology, Department of Oncology and Radiotherapy, Faculty of Medicine and University Hospital Hradec Kralove.

Methods:
Overview study focused on analysis of data of primary fallopian tube cancer.

Conclusion:
The incidence of primary fallopian tube cancer was thought to be very low in the past but it is very difficult to assess the primary origin in the case of advanced disease (ovary versus fallopian tube). Tumorogenic potential of endosalpinx in relation to epithelial tumours is much more bigger. According to the current knowledge, the vast majority of high-grade serous carcinomas of the “ovary“ in fact arise in the mucosa of fimbrial portion of fallopian tube.

Keywords:
primary fallopian tube cancer – ovarian cancer – BRCA mutation – risk factors – paraaortic lymphadenectomy

Zdroje

1. Alvarado-Cabrero, I., Stolnicu, S., Kiyokawa, T., et al. Carcinoma of the fallopian tube: Results of a multi-institutional retrospective analysis of 127 patients with evaluation of staging and prognostic factors. Ann Diagn Pathol, 2013, 17, p. 159–164.

2. Aziz, S., Kuperstein, G., Rosen, B., et al. A genetic and epidemiological study of carcinoma of the fallopian tube. Gynecol Oncol, 2001, 80, p. 341–345.

3. Brose, MS., Rebbeck, TR., Calzone, KA., et al. Cancer risk estimates for BRCA1 mutation carriers identified in a risk evaluation program. J Natl Cancer Indy, 2002, 94, p.1365–1372.

4. Cibula, D., Petruželka, L., et al. Onkogynekologie. Praha: Grada Publishing, 2009, s. 575–579.

5. D'Angelo, E., Prat, J. Classification of ovarian carcinomas based on pathology and molecular genetics. Clin Trans Oncol, 2010, 12, p. 783–787.

6. Deffieux, X., Morice, P., Thoury, A., et al. Anatomy of pelvic and para-aortic nodal spread in patients with primary fallopian tube carcinoma. J Am Coll Surg, 2005, 200, p. 45–48.

7. Finch, A., Shaw, P., Rosen, B., et al. Clinical and pathologic findings of prophylactic salpingo-oophorectomies in 159 BRCA1 and BRCA2 carriers. Gynecol Oncol, 2006, 100, p. 58–64.

8. Folkins, AK., Longacre, TA. Hereditary gynaecological malignancies: advances in screening and treatment. Histopathology, 2013, 62, p. 2–30.

9. Gadducci, A., Landoni, F., Sartori, E., et al. Analysis of treatment failures and survival of patiens with fallopian tube carcinoma: A Cooperative Task Force (CTF) study. Gynecol Oncol, 2001, 81, p. 150–159.

10. Hu, CY., Taymor, ML., Hertig, AT. Primary carcinoma of the fallopian tube. Am J Obstet Gynecol, 1950, 59, p. 58–67.

11. Kurman, RJ., Shieh, I. Molecular pathogenesis and extraovarian origin of epithelial ovarian cancer – shifting the paradigm. Hum Pathol, 2011, 42, p. 918–931.

12. Kurman, RJ., Vang, R., Junge, J., et al. Papillary tubal hyperplasia: the putative precursor of ovarian atypical proliferating (borderline) serous tumors, noninvasive implants, and endosalpingiosis. Am J Surg Pathol, 2011, 35, p. 1605–1614.

13. Leeper, K., Garcia, R., Swisher, E., et al. Pathologic findings in prophylactic oophorectomy specimens in high-risk women. Gynecol Oncol, 2002, 87, p. 52–56.

14. Medeiris, F., Muto, MG., Lee, Y., et al. The tubal fimbria is a preferred site for early adenocarcinoma in women with familial ovarian cancer syndrome. Am J Surg Pathol, 2006, 30, p. 230–236.

15. Moore, KN., Moxley, KM., Fader, AN., et al. Serous fallopian tube carcinoma: A retrospective, multi-institutional case-control comparison to serous adenocarcinoma of the ovary. Gynecol Oncol, 2007, 107, p. 398–407.

16. Piek, JM., vanDiest, PJ., Zweemer, RP., et al. Dysplastic changes in prophylactically removed fallopian tubes in women predisposed to developing ovarian cancer. J Pathol, 2001, 195, p. 451–456.

17. Piek, JM., Verheijen, RH., Kenemens, P., et al. BRCA 1/2-related ovarian cancers are of tubal origin: A hypothesis. Gynecol Oncol, 2003, 90, p. 49.

18. Prat, J. Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features. Virchows Arch, 2012, 460, p. 237–249.

19. Sedlis, A. Carcinoma of the fallopian tube. Surg Clin North Am, 1978, 58(1), p. 121–129.

20. Sinha, AC. Hydrops tubae profluens as a presenting symptom in primary carcinoma of the fallopian tube. Br Med J, 1959, 2(5158), p. 976–982, p. 996–1001.

21. Sobol, H., Jacquemier, J., Bonaiti, C., et al. Fallopian tube cancer as a feature of BRCA1-associated syndromes. Gynecol Oncol, 2000, 78, p. 263–266.

22. Stewart, SL., Wike, JM., Foster, Sl., et al. The incidence of primary fallopian tube cancer in United States. Gynecol Oncol, 2007, 107, p. 392–397.

23. Špaček, J., Petera, J., Tesařík, Z. Význam klinických prognostických faktorů v léčbě ovariálního karcinomu. Čes Gynek, 2002, 67, s. 280–285.

24. Špaček, J., Jílek, P., Petera, J., et al. Histopatologické prognostické faktory, sérové markery a vybrané molekulárně bio-logické faktory u ovariálního karcinomu. Čes Gynek, 2002, 67, s. 343–349.

25. Špaček, J., Veselský, Z., Tošner, J., et al. Paraaortální lymfadenektomie v gynekologii. Teoretické principy, základní postupy a praktická doporučení. Čes Gynek, 2003, 68, p. 99–105.

26. Tavassoli, FA., Devilee, P. (eds.). World Health Organization Classification of Tumours. Pathology and genetics of tumours of the breast and female genital organs. Lyon: IARC Press, 2003, p. 203–216.

27. Vang, R., Shih, I., Kurman, RJ. Fallopian tube precursors of ovarian low- and high-grade serous neoplasms. Histopathology, 2013, 62, p. 44–58.

28. Zweemer, RP., van Diest, PJ., Verheijen, RH., et al. Molecular evidence linking primary cancer of the fallopian tube to BRCA1 germline mutations. Gynecol Oncol, 2000, 76, p. 45–50.