Histopathological changes in placental tissue with connection to chosen clinical cases in obstetrics

Česká verzia

Authors: V. Harazím ¹; D. Skanderová ²
Authors place of work: Gynekologicko-porodnické oddělení, Městská nemocnice Ostrava, p. o., prim. MUDr. M. Ožana
Published in the journal: Ceska Gynekol 2016; 81(5): 336-341

Summary

Objective:
Evaluation of clinical relevance of histopathological examination on the basis of macroscopic and microscopic analyses of changes in placentas in chosen clinical cases.

Design:
Summarizing article.

Setting:
Department of Obstetrics and Gynecology and Department of Pathology, City Hospital in Ostrava.

Methods:
In this summarizing article we are presenting histopathological changes in placental tissues in connection with chosen clinical cases of obstetrics studied in the Department of Gynecology and Obstetrics in City Hospital in Ostrava from January to August 2015.

After processing, placentas were examined via light microscope in the Department of Pathology. Over the period mentioned above, more than 80 human placentas were examined and compared. From found histopathological changes and their comparison with clinical cases we can deduce their straight connection to premature birth.

Conclusion:
The clinical relevance of histopathological examination of placenta was proven from the view of obstetrician, specifically in cases of pathological pregnancy or birth and preterm birth.

Keywords:
placenta, pathology, histopathological examination of placenta, microscopic changes of placenta in preterm birth

Zdroje

1. Altshuler, G. Chorangiosis. An important placental sign of neonatal morbidity and mortality. Arch Pathol Lab Med, 1984, 108, p. 71–74.

2. Altuncu, E., Akman, İ., Kotıloğlu, E., et al. The relationship of placental histology to pregnancy and neonatal characteristics in preterm infants. J Turkish-German Gynecol Ass, 2008, 9(1).

3. Baergen, RN. Manual of pathology of the human placenta, 2nd ed. New York: Springer, 2011.

4. Benirschke, K., Kaufmann, P., Baergen, R. Pathology of the human placenta. 5th ed. New York: Springer, 2006, p. 1050.

5. Fristch, MK., Mukherjee, A., Chan, AC., et al. The placental distal villous hypoplasia pattern: Interobserver agreement and automated fractal dimension as an objective metric. Pediatr Dev Pathol, 2016, 19(1), p. 31–36.

6. Hájek, Z., Čech, E., Maršál, K., et al. Porodnictví 3., zcela přepracované a doplněné vyd. Grada, 2014, s. 312.

7. Hornychova, H., Matejkova, A., Kacerovsky, M. Practical comments on examination of placenta in the second and third trimester of gravidity, Cesk Patol, 2015, 51(2), p. 74–79.

8. Kacerovsky, M., Musilova, I., Andrys, C., et al. Prelabor rupture of membranes between 34 and 37 weeks: the intraamniotic inflammatory response and neonatal outcomes. Am J Obstet Gynecol, 2014, 210(4), p. 325.e1–325.e10.

9. Redline, RW. Placental pathology: a systematic approach with clinical correlations. Placenta, 2008, 29 (Suppl A), p. 586–591.

10. Redline, RW. Villitis of unknown etiology: noninfectious chronic villitis in the placenta. Hum Pathol, 2007, 38(10), p. 1439–1446.

11. Roescher, AM., Timmer, A., Hitzert, MM., et al. Placental pathology and neurological morbidity in preterm infants during first two weeks after birth. Early Hum Dev, 2014, 1, p. 21–25.

12. Salafia, CM., Weigl, C., Silberman, L. The prevalence and distribution of acute placental inflammation in uncomplicated term pregnancies. Obstet Gynecol, 1989, 73(3Pt 1), p. 383–389.

13. Silverberg, SG. Surgical patohology and cytopthology. Vol. 3, third ed. Churchil Livingstone, 1997, p. 2593–2628.

14. Skanderová, D., Haferník, J., Gattnarová, Z. Cyto-morfologický den: sborník příspěvků z konference: 9. 10. 2015, Morfologické změny placenty u předčasně narozených dětí, s. 25–29.

15. Stallmach, T., Hebisch, G. Rescue by birth: defective placental maturation and late fetal mortality obstetrics. Gynecology, 2001, 4, p. 505–509.

16. Tyson, R., Barton, C. The intrauterine growth restricted fetus and placenta evaluation. Semin Perinatol, 2008, 32(3), p. 166–171.

17. Vogel, M. Pathologie der Plazenta: Spätschwangerschaft und fetoplazentare Einheit. In: Klöppel, G., Kreipe, H., Remmele, W., eds. Pathologie. Heidelberg: Springer-Verlag, 2013, S. 519–539.

18. Vedmedovska, N., Rezeberga, D., Teibe, U., et al. Placental pathology in fetal growth restriction. Eur J Obstet Gynecol Reprod Biol, 2011, 155(1), p. 36–40.

19. Vedmedovska, N., Rezeberga, D., Teibe, U., et al. Microscopic lesions of placenta and Doppler velocimetry related to fetal growth restriction. Arch Gynecol Obstet, 2011. 284(5), p. 1087–1093.