Carcinosarcoma of the endometrium with melanocytic differentiation, case report
Authors:
D. Berezovskiy; P. Vlasák; J. Kosťun; J. Bouda; Jiří Presl
Authors place of work:
Gynekologicko-porodnická klinika LF UK a FN, Plzeň, přednosta doc. MUDr. Z. Novotný, CSc.
Published in the journal:
Ceska Gynekol 2017; 82(5): 390-395
Summary
Objective:
The case report presents a case of 60-year old woman with a rare malignant mixed Müllerian tumor with melanomatous differentiation diagnosed from a histology after cervical polyp ablation and curettage.
Design:
Case report.
Setting:
Department of gynecology and obstetrics, University Hospital in Pilsen.
Conclusion:
Carcinosarcoma, previously malignant mixed Müllerian tumor, is a very rare aggressive endometrial carcinoma with low incidence, which typically occurs among older women and commonly affects the uterine body and cervix. Clinically, the carcinosarcoma is impossible to be distinguished from endometrial carcinoma or uterine sarcoma and the definitive diagnosis can only be made based on histological examination.
Keywords:
carcinosarkoma, malignant mixed Müllerian tumor, diagnostics, radical surgery, histology, relapse
Zdroje
1. Amant, F., Moerman, P., Davel, GH., et al. Uterine carcinosarcoma with melanocytic differentiation. Int J Gynecol Pathol, 2001, 20(2), p. 90–186.
2. Arend, R., Doneza, JA., Wright, JD. Uterine carcinosarcoma. Curr Opin Oncol, 2011, 23, p. 531.
3. Bansal, N., Herzog, TJ., Burke, W., et al. The utility of preoperative endometrial sampling for the detection of uterine sarcomas. Gynecol Oncol, 2008, 110, p. 43.
4. Bodner-Adler, B., Bodner, K., Obermair, A., et al. Prognostic parameters in carcinosarcomas of the uterus: a clinico-pathologic study. Anticancer Res, 2001, 21, p. 3069.
5. Callister, M., Ramondetta, LM., Jhingran, A., et al. Malignant mixed Müllerian tumors of the uterus: analysis of patterns of failure, prognostic factors, and treatment outcome. Int J Radiat Oncol Biol Phys, 2004, 58, p. 786.
6. Dave, KS., Chauhan, A., Bhansali, R., et al. Uterine carcinosarcomas: 8-year single center experience of 25 cases. Indian J Med Paediatr Oncol, 2011, 32, p. 149.
7. Fotiou, S., Hatjieleftheriou, G., Kyrousis, G., et al. Long-term tamoxifen treatment: a possible aetiological factor in the development of uterine carcinosarcoma: two case-reports and review of the literature. Anticancer Res, 2000, 20, p. 2015.
8. Frühauf, F., Dvořák, M., Haaková, L., et al. Ultrazvukový staging karcinomu endometria - doporučená metodika vyšetření. Čes Gynek, 2014, 79, 6, s. 76-466.
9. Gonzalez Bosquet, J., Terstriep, SA., Cliby, WA., et al. The impact of multi-modal therapy on survival for uterine carcinosarcomas. Gynecol Oncol, 2010, 116, p. 419.
10. Kajo, K., Zubor, P., Spacek, J., Ryska, A., et al. Carcinosarcoma of the uterus with melanocytic differentiation. Pathol Res Pract, 2007, 203, 10, p. 753.
11. Nemani, D., Mitra, N., Guo, M., Lin, L. Assessing the effects of lymphadenectomy and radiation therapy in patients with uterine carcinosarcoma: a SEER analysis. Gynecol Oncol, 2008, 111, p. 82.
12. Pothuri, B., Ramondetta, L., Martino, M., et al. Development of endometrial cancer after radiation treatment for cervical carcinoma. Obstet Gynecol, 2003, 101, p. 941.
13. Salazar, OM., Bonfiglio, TA., Patten, SF., et al. Uterine sarcomas: natural history, treatment and prognosis. Cancer, 1978, 42, p. 1152.
14. Tirumani, SH., Ojili, V., Shanbhogue, AK., et al. Current concepts in the imaging of uterine sarcoma. Abdom Imaging, 2013, 38, p. 397.
15. Treilleux, T., Mignotte, H., Clement-Chassagne, C., et al. Tamoxifen and malignant epithelial-nonepithelial tumours of the endometrium: report of six cases and review of the literature. Eur J Surg Oncol, 1999, 25, p. 477.
16. Wolfson, AH., Brady, MF., Rocereto, T., et al. A gynecologic oncology group randomized phase III trial of whole abdominal irradiation vs. cisplatin-ifosfamide and mesna as post-surgical therapy in stage I-IV carcinosarcoma of the uterus. Gynecol Oncol, 2007, 107, p. 177.
17. Zelmanowicz, A., Hildesheim, A., Sherman, ME., et al. Evidence for a common etiology for endometrial carcinomas and malignant mixed mullerian tumors. Gynecol Oncol, 1998, 69, p. 253.
Štítky
Paediatric gynaecology Gynaecology and obstetrics Reproduction medicineČlánok vyšiel v časopise
Czech Gynaecology
2017 Číslo 5
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