Sentinel lymph node mapping in endometrial cancer – robotic vs. laparoscopic detection system

Česká verzia

Authors: M. Michal; P. Valha; M. Velemínský
Authors place of work: Gynekologicko-porodnické oddělení, Nemocnice České Budějovice, a. s.
Published in the journal: Ceska Gynekol 2023; 88(3): 157-161
Category: Original Article
doi: https://doi.org/10.48095/cccg2023157

Summary

Objective: Comparison of systems to detect sentinel lymph node in endometrial carcinoma using indocyanine green. Robotic Firefly Da Vinci fluorescence imaging system (Intuitive Surgical Inc., Sunnyvale, CA, USA) vs. laparoscopic Novadaq Pinpoint near-infrared imaging system (Novadaq, Ontario, Canada). Material and method: Fifteen patients with stage I endometrial cancer underwent sentinel lymph node biopsy after intracervical application of indocyanine green. For all of them, the detection was performed sequentially using both evaluated devices. The detection rate, identification match and extent of imaging of the lymphatic system were evaluated. Results: The detection rate of both systems verified on a set of patients was identical, the detected sentinel nodes were identical, and the lymphatic system was shown to the same extent. The quality of the display and overall user-friendliness is different due to the applied technologies. Conclusion: Both systems used in minimally invasive surgery provide excelent perioperative imaging of the lymphatic system.

Keywords:

indocyanine green – endometrial cancer – sentinel lymph node – Da Vinci Firefly – Novadaq Pinpoint

Zdroje

1. Dušek L, Mužík J, Kubásek M et al. Epidemiologie zhoubných nádorů v České republice. 2022 [online]. Dostupné z: http: //www.svod.cz/?sec=analyzy.

2. Minář L, Weinberger V, Kysela P. Komplikace radikálních onkogynekologických operací. Ceska Gynekol 2010; 75 (4): 346–352.

3. Bogani G, Murgia F, Ditto A et al. Sentinel node mapping vs. lymphadenectomy in endometrial cancer: a systematic review and meta-analysis. Gynecol Oncol 2019; 153 (3): 676–683. doi: 10.1016/j.ygyno.2019.03.254.

4. Concin N, Matias-Guiu X, Vergote I et al. ESGO/ESTRO/ESP guidelines for the management of patients with endometrial carcinoma. Int J Gynecol Cancer 2021; 31 (1): 12–39. doi: 10.1136/ijgc-2020-002230.

5. Dundr P, Cibula D, Doležel M et al. Molekulární testování u karcinomu endometria – společné doporučení ČOS, onkogynekologické sekce ČGPS, SROBF a SČP ČLS JEP. Ceska Gynekol 2021; 86 (4): 264–272. doi: 10.48095/cccg2021264.

6. Rozenholc A, Samouelian V, Warkus T et al. Green versus blue: randomized controlled trial comparing indocyanine green with methylene blue for sentinel lymph node detection in endometrial cancer. Gynecol Oncol 2019; 153 (3): 500–504. doi: 10.1016/j.ygyno.2019.03.103.

7. Frumovitz M, Plante M, Lee PS et al. Near-infrared fluorescence for detection of sentinel lymph nodes in women with cervical and uterine cancers (FILM): a randomised, phase 3, multicentre, non-inferiority trial. Lancet Oncol 2018; 19 (10): 1394–1403. doi: 10.1016/S14 70-2045 (18) 30448-0.

8. Geppert B, Lönnerfors C, Bollino M et al. A study on uterine lymphatic anatomy for standardization of pelvic sentinel lymph node detection in endometrial cancer. Gynecol Oncol 2017; 145 (2): 256–261. doi: 10.1016/j.ygyno.2017. 02.018.

9. Persson J, Geppert B, Lönnerfors C et al. Description of a reproducible anatomically based surgical algorithm for detection of pelvic sentinel lymph nodes in endometrial cancer. Gynecol Oncol 2017; 147 (1): 120–125. doi: 10.1016/ j.ygyno.2017.07.131.

10. Persson J, Salehi S, Bollino M et al. Pelvic Sentinel Lymph Node Detection in High- -Risk Endometrial Cancer (SHREC-Trial) -the final step towards a paradigmshift in surgical staging. Eur J Cancer 2019; 116: 77–85. doi: 10.1016/ j.ejca.2019.04.025.

11. Leitao MM Jr. Sentinel lymph node mapping in patients with endometrial carcinoma: less can be more. Curr Obstet Gynecol Rep 2016; 5 (4): 279–285. doi: 10.1007/s13669-016-01 78-7.

12. Lin H, Ding Z, Kota VG et al. Sentinel lymph node mapping in endometrial cancer: a systematic review and meta-analysis. Oncotarget 2017; 8 (28): 46601–46610. doi: 10.18632/onco target.16662.

13. Ditto A, Casarin J, Pinelli C et al. Hysteroscopic versus cervical injection for sentinel node detection in endometrial cancer: a multicenter prospective randomised controlled trial from the Multicenter Italian Trials in Ovarian cancer (MITO) study group. Eur J Cancer 2020; 140: 1–10. doi: 10.1016/j.ejca.2020.08.030.

14. Ruiz R, Gorostidi M, Jaunarena I et al. Maximizing sentinel node detection in endometrial cancer with dual cervical and transcervical fundal indocyanine green injection: 5-year single--center prospective study. Eur J Obstet Gynecol Reprod Biol 2021; 261: 59–64. doi: 10.1016/ j.ejogrb.2021.04.015.

15. Kumar S, Podratz KC, Bakkum-Gamez JN et al. Prospective assessment of the prevalence of pelvic, paraaortic and high paraaortic lymph node metastasis in endometrial cancer. Gynecol Oncol 2014; 132 (1): 38–43. doi: 10.1016/ j.ygyno.2013.10.002.

16. Lopez Labrousse MI, Frumovitz M, Guadalupe Patrono M et al. Sentinel lymph node mapping in minimally invasive surgery: role of imaging with color-segmented fluorescence (CSF). Gynecol Oncol 2017; 146 (3): 676–677. doi: 10.1016/j.ygyno.2017.06.009.