Musculoskeletal manifestations in celiac disease
Authors:
L. Franeková; T. Philipp; M. Sedláčková
Authors place of work:
Revmatologické a rehabilitační oddělení Fakultní Thomayerovy nemocnice, Praha
Published in the journal:
Čes. Revmatol., 15, 2007, No. 4, p. 190-196.
Category:
Overview Reports
Summary
Celiac disease is an autoimmune disorder induced by gliadin fraction of gluten (a protein that is in grain of wheat, rye, barley and oat) in genetically predisposed individuals. Enteric mucosa is primarily affected by the disease. The diagnosis is based on histological manifestation of lymphoplasmocellular infiltrates and various degrees of mucosa atrophy and hyperplastic crypts. Clinical manifestations are substantially variable – ranging from diarrhoea and fatigue, loss of weight and other manifestations of malabsorption to nonspecific manifestations (meteorism, abdominal pain) or any alimentary manifestation. The only manifestation of the disease may be osteoporosis, osteomalacia, neurological disturbances, and gynecological, dermal or joint manifestations – mostly non-erosive symmetric polyarthritis affecting shoulders, knees and hips and possibly axial involvement. The authors discuss usefulness of celiac specific antibodies for the diagnosis of celiac disease, musculoskeletal manifestations (mostly osteoporosis and joint involvement) and occurrence of celiac disease among patients with systemic connective tissue diseases.
Key words:
celiac disease, osteoporosis, osteomalacia, arthritis, antibodies
Zdroje
1. Kagnoff MF. Overview and pathogenesis of celiac disease. Gastroenterology 2005; 128, Suppl 1: 10–18.
2. Heel DA, West J. Recent advances in coeliac disease. Gut 2006; 55: 1037–1046.
3. Rewers M. Epidemiology of celiac disease: What are the prevalence, incidence, and progression of celiac disease? Gastroenterology 2005; 128, Suppl 1: 47–51.
4. Mäki M, Collin P. Celiac disease. Lancet 1997; 349: 1755–1759.
5. Kohout P. Diagnostika a léčba celiakie. Interní Med 2006; 7 + 8: 324–326.
6. Pietzak MM. Follow up of patient with celiac disease: achieving compliance with treatment. Gastroenterology 2005; 128, Suppl 1: 135–141.
7. Kupper S. Dietary guidelines and implementation for celiac disease. Gastroenterology 2005; 128, Suppl 1: 121–127.
8. Catassi C, Bearzi I, Holmes GK. Association of celiac disease and intestinal lymphomas and other cancers. Gastroenterology 2005; 128, Suppl 1: 79–86.
9. Holmes GK, Prior P, Lane MR, et al. Malignancy in celiac disease – efect of gluten free diet. Gut 1989; 30: 333–338.
10. Collin P. Should adults be screened for celiac disease? What are the benefits and harms of screening? Gastroenterology 2005; 128, Suppl 1: 104–108.
11. Ilavská A, Paulovičová E, Mikulecký M. Význam vyšetrenia sérologických markerov u pacientov s celiakiou. Čas Lék čes 2002; 141(15): 487–490.
12. Liu E, Rewers M, Eisenbarth GS. Genetic testing: who should do the testin and what is the role of genetic testing in the setting of celiac disease. Gastroenterology 2005; 128, Suppl 1: 33–37.
13. Ivarsson A. Swedish epidemic of coeliac disease explored using an epidemiological approach some lessons to be learnt. Best Pract Res Clin Gastroenterol 2005; 19: 425–440.
14. Bureš J, Horáček J, et al. Základy vnitřního lékařství. Praha: Galén, 2003: 294–297.
15. Fanciulli G, Tomasi PA, Caucci F, et al. Screening for celiac disease in patients with autoimmune thyroid disease: from reseach studies to daily clinical practice. Ann Ital Med Int 2005; 20: 39–44.
16. Murray JA. Celiac disease in patients with an affected member, type 1 diabetes, iron–deficiency or osteoporosis? Gastroenterology 2005; 128, Suppl 1: 52–56.
17. Michaelson G, Gerden B, Hagforsen E, et al. Psoriasis patients with antibodies to gliadin can be improved by a gluten-free diet. Br J Dermatol 2000; 142: 44–51.
18. Dewar DH, Ciclitira PJ. Clinical features and diagnosis of celiac disease. Gastroenterology 2005; 128, Suppl 1: 19–24.
19. Green PHR. The many faces of celiac disease: clinical presentation of celiac disease: clinical presentation of celiac disease in the adult population. Gastroenterology 2005;128, Suppl 1: 74–78.
20. Bushara KO. Neurologic manifestation of celiac disease. Gastroenterology 2005;128, Suppl 1: 92–97.
21. Holden W, Orchard T, Wordsworth P. Enteropathic arthritis. Rheum Dis Clin N Am 2003; 29: 513–530.
22. Zone JJ. Skin manifesation of celiac disease. Gastroenterology 2005; 128, Suppl 1: 87–91.
23. Duggan JM, Duggan AE. Liver in celiac disease. Aliment Pharmacol Ther 2005; 21: 515–518.
24. Tata LJ, Card TR, Logan RFA, et al. Fertility and pregnancy – related events in women with celiac disease: a population – based cohort study. Gastroenterology 2005; 128, Suppl 1: 849–855.
25. Rostom A, Dubé C, Cranney A, et al. The diagnostic accurancy of serologic tests for celiac disease: a systematic review. Gastroenterology 2005; 128, Suppl 1: 38–46.
26. Hill ID. What are the sensitivity and specificity of serologic tests for celiac disease? Do sensitivity and specificity vary in different populations? Gastroenterology 2005; 128, Suppl 1: 25–32.
27. Kocna P, Vaníčková Z, Perušičová J, Dvořák M. Tissue transglutaminase – serology markers for celiac disease. Clin Chem Lab Med 2002; 40 (5): 485–492.
28. Carroccio A, Cavataio F, Iacono G, et al. IgA antiendomysial antibodies on the umbilical cord in diagnosis celiac disease. Sensitivity, specificity and comparative evaluation with the traditional kit. Scand J Gastroenterol 1996; 31: 759–763.
29. Zintzaras E, Germenis AE. Performance o antibodies againts tissue transglutaminase for the diagnosis of celiac disease: meta-analyses. Clin Vaccine Immunol 2006; 13: 187–192.
30. Lerner A, Kumar V. Immunological diagnosis of childhood coeliac disease: comparison between antigladin, antireticulin and antiendomysial antibodies. Clin Exp Immunol 1994; 95: 78–82.
31. Prince HE. Evolution of the INOVA diagnostics enzyme-linked immunosorbent assay kits for measuring serum immunoglobulin G (IgG) and IgA to deamidated gliadin peptides. Clin Vaccine Immunol 2006; 13 (1): 150–151.
32. Valeski JE, Kumar V, Beutner EH, et al. Immunology of celiac disease: tissue and species specifity of endomysial and reticulin antibodies. Int Arch Allergy Appl Immunol 1990; 93: 1–7.
33. Vančiková Z, Chlumecký V, Sokol D, et al. The serologic screening for celiac disease in the general population (blood donors) and in some high-risk groups of adults (patients with autoimmune disease, osteoporosis and infertility) in the Czech Republic. Folia Microbiol 2002; 47: 753–758.
34. Bourne JT, Kumar P, Huskisson EC, et al. Arthritis and coeliac disease. Ann Rheum Dis 1985; 44: 592–598.
35. Szodoray P, Barta Z, Lakos G, et al. Coeliac disease in Sjögren’s syndrome – a study of 111 Hungarian patients. Rheumatol Int 2004; 24: 278–282.
36. Dubé C, Rostom A, Sy R, et al. Prevalence of celiac disease in average-risk and at-risk Western European populations: a systematic review. Gastroenterology 2005, 128, Suppl 1: 57–67.
37. Sanders DS, Patel D, Khan FB, et al. Case – finding for adult celiac disease in patients with reduced bone mineral density. Dig Ds Sci 2005; 50: 587–592.
38. Keaveny AP, Freaney R, McKenna MJ, et al. Bone remodeling indices and secondary hyperparathyroidism in celiac disease. Am J Gastroenterol 1996; 91 (6): 1226–1231.
39. Marsh MN. Bone disease and gluten sensitivity: time to act, to treat, and to prezent. Am J Gastroenterol 1994; 89, 2105–2107.
40. Selby PL, Davies M, Adams JE, et al. Bone loss in celiac is related to secondary hyperparathyroidism. J Bone Miner Res 1999; 14: 652–657.
41. Kocián J. Osteoporóza a osteomalacie. Praha: Triton, 1997: 59–65.
42. Kocián J. Sekundární osteopenie u gastrointestinálních chorob. Vntřní Lék 1993; 39: 125–131.
43. Mora S, Barera G, Beccio S, et al. Bone density and bone metabolism are normal after long- term gluten free diet in young celiac patiens. Am J Gastroenterol 1999; 94: 398–403.
44. Broulík P. Osteoporóza. Praha: Maxdorf Jessenius, 1999: 105–116.
45. Žlnay D, Mateička F, Rovenský J. Séronegativní spondylartritidy. V: Pavelka K, Rovenský J. Klinická revmatologie. Praha: Galén, 2003; 345–389.
46. Uksila J, Toivanen P, Granfors K. Enteric infections and arthritis: bacteriological aspects. In: Calin A, Taurog J. Spondylarthritides. Oxford : Oxford University Press, 1998: 167–177.
47. Adelizzi RA, Pecora AA, Chiesa JC. Celiac disease: case report with an associated with arthropathy. Am J Gastroenterol 1982; 77: 481–483.
48. Lubrano E, Ciacci C, Ames PRJ, et al. Arthritis of coeliac disease: prevalence and pattern in 200 adult patients. Br J Rheumatol 1996; 35: 1314–1318.
49. Slot O, Locht H. Arthritis as presenting symptom in silent adult coeliac disease. Scand J Rheumatol 2000; 29: 260–263.
50. Summers GD, Hankey GL, Holmes GKT. Oligoartritis – a presenting feature of occult coeliac disease. Br J Rheumatol 1993; 32: 262.
51. Collin P, Korpela M, Hällström O, et al. Rheumatic complaints as a presenting symptom in patients with coeliac disease. Scand J Rheumatol 1992; 21: 20–23.
52. Mäki M, Hällström O, Viander M, et al. Reticulin antibody, arthritis and coeliac disease in children. Lancet 1988; 1: 479–480.
53. Borg AA, Dawes PT, Swan CH, et al. Persistent monoarthritis and ocult coeliac disease. Postgradual Med J 1994; 70: 51–53.
54. Usai P, Boi MF, Piga M, et al. Adult celiac disease is frequently associated with sacroiliitis. Dig Dis Sci 1995; 40: 1906–1908.
55. Luft LM, Barr SG, Martin LO, et al. Autoantibodies to tissue transglutaminase in Sjögren’s syndrome and related rheumatic disease. J Rheumatol 2003; 30: 2613–2619.
56. Iltanen S, Collin P, Korpela M, et al. Celiac disease and markers of celiac disease latency in patients with primary Sjögren’s synrome. Am J Gastroenterol 1999; 94: 1042–1046.
57. Stagi S, Giani T, Simonini G, et al. Thyroid function, autoimmune thyroiditis and coeliac disease in juvenile idiopathic arthritis. Rheumatology 2005; 44: 517–520.
Štítky
Dermatology & STDs Paediatric rheumatology RheumatologyČlánok vyšiel v časopise
Czech Rheumatology
2007 Číslo 4
Najčítanejšie v tomto čísle
- Rhabdomyolysis, a brief case report and commentary
- Hip joint destruction and secondary synovial chondromatosis in a patient with rheumatoid arthritis
- Musculoskeletal manifestations in celiac disease
- Procalcitonin in the diagnosis of bacterial infection in patients with autoimmune rheumatic diseases