Atypical Mycobacteriosis and Pitfalls of its Therapy
Authors:
M. Bodnárová 1; J. Štork 1; M. Kojanová 1; P. Ježek 2; V. Fišerová 2; M. Havelková 3; I. Pavlík 4
Authors place of work:
Dermatovenerologická klinika 1. LF UK a VFN, Praha
přednosta prof. MUDr. J. Štork, CSc.
1; Oddělení klinické mikrobiologie a parazitologie, Oblastní nemocnice Příbram a. s.
přednosta prim. MVDr. Petr Ježek
2; NRL pro mykobakerie, SZÚ Praha
vedoucí MUDr. Marta Havelková, CSc.
3; Referenční laboratoř pro paratuberkulózu a aviární tuberkulózu
Výzkumný ústav veterinárního lékařství, Brno
vedoucí prof. MVDr. Ivo Pavlík, CSc.
4
Published in the journal:
Čes-slov Derm, 83, 2008, No. 6, p. 305-309
Category:
Case Reports
Summary
Atypical mycobacteriosis (also called mycobacteriosis) is a non-tuberculous mycobacterial infection caused by opportunistic pathogenic species of mycobacteria. The case of 53-year-old woman with rare sporotrichoid form of skin infection caused by injury after the contact with aquarium fish followed by formation of multiple nodules with abscesses is presented. Histological examination supported the diagnosis of mycobacteriosis. After four months of unsuccessful antimicrobial therapy the causative agent Mycobacterium marinum was isolated. The patient was treated for eleven months with combined antibacterial therapy with ciprofloxacin and ethambutol based on the agent drug sensitivity on cultivation and surgical excisions of small persistent lesions. Difficulties in diagnostics and therapy, often due to failed isolation of the causative agent, are presented. Optimal targeted therapy is based on the sensitivity of isolated strain to antituberculotic and other antibacterial agents.
Key words:
atypical mycobacteriosis – sporotrichoid form – Mycobacterium marinum – diagnosis – targeted therapy
Zdroje
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Štítky
Dermatology & STDs Paediatric dermatology & STDsČlánok vyšiel v časopise
Czech-Slovak Dermatology
2008 Číslo 6
Najčítanejšie v tomto čísle
- Atypical Mycobacteriosis and Pitfalls of its Therapy
- Tinea capitis
- Mycobacteriosis in Fish and Risk of Human Infection
- Transepidermal Water Loss Measurement (TEWL)