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Successful Therapy of Erythrodermic Psoriasis with Efalizumab after Infliximab Discontinuation


Authors: M. Tichý;  D. Ditrichová
Authors place of work: Klinika chorob kožních a pohlavních LF UP a FN Olomouc přednostka doc. MUDr. Dagmar Ditrichová, CSc.
Published in the journal: Čes-slov Derm, 84, 2009, No. 4, p. 200-203
Category: Pharmacologyand Therapy, Clinical Trials

Summary

A lack of efficacy and serious adverse events of biological drugs are reasons to change the therapeutic strategy in psoriasis. Switch of biologicals which are used for the treatment of psoriasis does not have strict rules and partly depends on experience of dermatologist. A case of patient with erythrodermic psoriasis successfuly treated with efalizumab after infliximab discontinuation for severe adverse reaction is reported.

Key words:
psoriasis – infliximab – efalizumab


Zdroje

1. BENÁKOVÁ, N., ŠTORK, J. Léčba psoriázy biologiky. Konsensuální doporučené postupy České dermatovenerologické společnosti ČLS JEP 2006. Čes-slov Derm, 2006, 81(4), s. 1-11.

2. CALABRESE, LH. Molecular differences in anticytokine therapies. Clin Exp Rheumatol, 2003, 21, p. 241-248.

3. GOTTLIEB, AB., EVANS, R., LI, S. et al. Infliximab induction therapy for patients with severe plaque psoriasis: a randomized, double-blind, placebo-controlled trial. J Am Acad Dermatol, 2004, 51, p. 534-542.

4. Léčba psoriázy efalizumabem (Raptiva). Suplement. Čes-slov. Derm, 2008, č.1, 35s.

5. NEWLAND, MR., WEINSTEIN, A., KERDEL, F. Rapid response to infliximab in severe pustular psoriasis, von Zumbusch type. Int J Dermatol, 2002, 41, p. 449-452.

6. RONGIOLETTI, F., BORENSTEIN, M., KIRSNER, R. et al. Erythrodermic, recalcitrant psoriasis: clinical resolution with infliximab. J Dermatolog Treat, 2003, 14, p. 222-225.

7. TICHÝ, M., DITRICHOVÁ, D. Biologika v léčbě těžkých forem psoriázy. Dermatolog praxi, 2007, 1(1), s. 19-21.

8. TICHÝ, M., DITRICHOVÁ, D. Těžká forma chronické ložiskové psoriázy léčená efalizumabem. Čes-slov Derm, 2008, 83(1), s. S31-S32

Štítky
Dermatology & STDs Paediatric dermatology & STDs
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