Frequency of Food Allergy to Egg Proteins in Atopic Patients Older than 14 Years
Authors:
J. Čelakovská 1; K. Ettlerová 2; K. Ettler 1; J. Vaněčková 1; J. Bukač 3
Authors place of work:
Klinika nemocí kožních a pohlavních FN a LF UK Hradec Králové
přednosta doc. MUDr. Karel Ettler, CSc.
1; Ambulance klinické imunologie a alergologie, Hradec Králové
vedoucí MUDr. Květuše Ettlerová
2; Ústav lékařské biofyziky LF UK Hradec Králové
přednosta doc. Ing. Josef Hanuš, CSc.
3
Published in the journal:
Čes-slov Derm, 85, 2010, No. 5, p. 264-273
Category:
Clinical and laboratory Research
Summary
Aim:
The aim of our study was to investigate the frequency of egg proteins allergy in adolescent and adult patients with atopic eczema and its possible role in disease flares.
Methods:
Group of 179 atopic patients older than 14 years was investigated for the egg allergy (history, skin prick tests, serum specific IgE and atopy patch tests were performed) and its significance was evaluated. In patients with at least one positive test of either yolk or egg white the open exposure test with an egg was performed folloving hypoallergenic elimination diet. The egg allergy was diagnosed in case of positive result of the open exposure test and the evaluation of patient’s history.
Results:
Egg protein allergy was confirmed in 11 patients (6%). Both early reactions (in 2,7% of patients oral allergy syndrome, itching and asthma) and worsening of atopic eczema (in 3, 3% of patients) were noticed. Positivity of serum specific IgE and prick tests to egg proteins (in 34% of patients) in great part of them (in 28%) did not correlate with clinical symptoms of allergy. Atopy patch tests revealed egg allergy in 1% of IgE non-reactive patients.
After egg eliminaton the skin symptoms improved especially in those with late reaction in open exposure tests.
Conclusion:
To diagnose food allergy in atopic patients the complete diagnostic process including exposure test after elimination diet is necessary.
Key words:
egg protein allergy – atopic eczema – skin prick tests – specific IgE – atopy patch tests – open exposure test
Zdroje
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Štítky
Dermatology & STDs Paediatric dermatology & STDsČlánok vyšiel v časopise
Czech-Slovak Dermatology
2010 Číslo 5
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