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Calciphylaxis with Skin Ulcers. Case Report


Authors: M. Horáková 1;  L. Pock 2;  I. Bureš 3;  E. Husáková 3
Authors place of work: Kožní oddělení, Pardubická krajská nemocnice primář MUDr. David Stuchlík 1;  Dermatohistopatologická laboratoř Doc. MUDr. Lumír Pock, CSc., s. r. o., Praha vedoucí pracoviště doc. MUDr. Lumír Pock, CSc. 2;  Geriatrické centrum, Pardubická krajská nemocnice primář MUDr. Ivo Bureš 3
Published in the journal: Čes-slov Derm, 87, 2012, No. 3, p. 98-101
Category: Case Reports

Summary

The article describes a case of multiple necrotic skin ulcers on the abdomen and on the lateral parts of thighs in a 72-year-old woman with insulin dependent diabetes mellitus and chronic renal failure without regular hemodialysis caused by histologically proven calciphylaxis with fatal progress. Authors present an overview of current knowledge on the treatment options.

Key words:
calciphylaxis – calcifications – ulcer – necrosis – uremia – sepsis – hemodialysis


Zdroje

1. ADROGUÉ, H. J., FRAZIER, M. R., ZELUFF, B. et al. Systemic Calciphylaxis Revisited. Am. J. Nephrol., 1981,1, p. 177–183.

2. BASILE, C., MONTANARO, A., MASI, M. et al. Hyperbaric oxygen therapy for calcific uremic arteriolopathy: a case series. J. Nephrol., 2002 Nov-Dec, 15, 6, p. 676–680.

3. BOLOGNIA, J. B., JORIZZO, J. L., RAPINI, R. P. Dermatology. 2nd ed., Spain: Mosby Elsevier, 2008, p. 654–655.

4. BRYANT, J. H., WHITE, W. H. A case of calcification of the arteries and obliterative andarteritis associated with hydronephrosis in a child aged six months. Guy’s Hospital Reports, 1898, 55, p. 17.

5. CALLEN, J. P., JORIZZO, J. L. et al. Dermatological signs of internal dinase. 4th ed., China: Saunders Elsevier, 2009, p. 306–307.

6. CETKOVSKÁ, P., PIZINGER, K., ŠTORK, J. Kožní změny u interních onemocnění. Praha: Grada Publishing, 2010, s. 101–103.

7. GUERRA, G., SHAH, R. C., ROSS, E. A. Rapid resolution of calciphylaxis with intravenous sodium thiosulfate and continuous venovenous haemofiltration using low calcium replacement fluid: case report. Nephrol. Dial. Transplant., 2005 Jun, 20, 6, p. 1260–1262.

8. ROGERS, N. M., COATES, T. H. Calcific uraemic arteriopathy: an update. Current. Opinion Nephrol. Hypertension, 2008, 17, p. 629–634.

9. SELYE, H. Calciphylaxis. Chicago: University of Chicago Press, 1962, p. 15–40.

10. TÖRÖK, L. Kožní projevy při chorobách vnitřních orgánů. Leipzig: J. A. Barth Verlag, Hünthig GmbH, Heidelberg, 1998, s. 179–180.

11. WANG, H. Y., YU, C. C., HUANG, C. C. Successful treatment of severe calciphylaxis in a hemodialysis patient using low-calcium dialysate and medical parathyroidectomy: case report and literature review. Ren. Fail., 2004 Jan, 26, 1, p. 77–82.

Štítky
Dermatology & STDs Paediatric dermatology & STDs
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