Pyoderma Gangrenosum in a Pregnant Patient. Case Report
Authors:
A. Bártlová 1; M. Salavec 1
Authors place of work:
Klinika nemocí kožních a pohlavních, Fakultní nemocnice a Lékařská fakulta v Hradci Králové, přednosta doc. MUDr. Miloslav Salavec, CSc.
Published in the journal:
Čes-slov Derm, 95, 2020, No. 6, p. 212-217
Category:
Case Reports
Summary
The authors present a case of a 34-year-old pregnant patient with confirmed diagnosis of pyoderma gangrenosum (PG). As systemic corticosteroid therapy had not resulted in lesion clearing, combined immunosupressive treatment (corticosteroids, cyclosporine A and mycophenolate mofetil) was administered that led to gradual healing of the lesions. Steroid and gestational diabetes developed as complications of therapy. Furthermore, ulcerative colitis was diagnosed year and a half after the appearance of skin lesions. The administration of infliximab led to remission of PG as well as ulcerative colitis and enabled the discontinuation of previous combined immosuppresive treatment. The article reviews recent knowledge of diagnostics and therapeutical approaches in this disease.
Keywords:
pyoderma gangrenosum – ulcerative dermatosis – pregnancy – combined immunosuppressive therapy – biologic therapy
Zdroje
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Štítky
Dermatology & STDs Paediatric dermatology & STDsČlánok vyšiel v časopise
Czech-Slovak Dermatology
2020 Číslo 6
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