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Combined Naevus with Pigmented Epithelioid Melanocytoma. Case Report


Authors: Z. Drlík 1,2;  L. Drlík 1;  L. Pock 3
Authors place of work: Dermatologická ambulance Mohelnice 1;  Klinika chorob kožních a pohlavních FN a LF UP Olomouc, přednosta odb. as. MUDr. Martin Tichý, Ph. D. 2;  Bioptická laboratoř Plzeň s. r. o., odborná vedoucí lékařka prof. MUDr. Alena Skálová, CSc. 3
Published in the journal: Čes-slov Derm, 96, 2021, No. 5, p. 230-233
Category: Dermatoscopy

Summary

The authors describe the case of a 38-year-old otherwise healthy male, followed after dysplastic naevi removal, who underwent an excision of a naevus with dark island in occipital region. Histologic examination showed combined compound melanocytic naevus and pigmented epithelioid melanocytoma, which has metastatic potential, but its clinical course is indolent. Subsequently a re-excision with additional margins and regional lymph nodes ultrasonography was performed, both with negative results. A brief review of current knowledge is presented.

Keywords:

treatment – combined melanocytic naevus – pigmented epithelioid melanocytoma – compound naevus


Zdroje

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2. DE OLIVEIRA, R. T. G., LANDMANN, G., LOCATELLI, D. S. et al. Pigmented epithelioid melanocytoma: A case report. J Cutan Pathol., 2020, 47, p. 109–112.

3. ISALES, M. C., MOHAN, L. S., OUAN, V. L. et al. Distinct Genomic Patterns in Pigmented Epithelioid Melanocytoma: A Molecular and Histologic Analysis of 16 Cases. Am J Surg Pathol., 2019, 43(4), p. 480–488.

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6. POCK, L., KOTRLÁ, M., DRLÍK, L. Klonální melanocytární névy. Čes-slov Derm, 2015, 90(1), s. 13–19.

7. TONČIĆ, R. J., SUSIC, S. L., CURKOVIC, D. et al. Pigmented Epithelioid Melanocytoma in Congenital Nevus of Medium Size in Children. Dermatol Pract Concept, 2020, 10(3), p. e2020067. DOI: https://doi. org/10.5826/dpc.1003a67.

8. YEH, I. New and evolving concepts of melanocytic nevi and melanocytomas. Modern Pathology, 2020, 33, p. 1–14.

9. ZEMBOWICZ, A., CARNEY, J. A., MIHM, M. C. Pigmented Epithelioid Melanocytoma. A Low-grade Melanocytic Tumor With Metastatic Potential Indistinguishable From Animal-type Melanoma and Epithelioid Blue Nevus. Am J Surg Path., 2004, 28(1), p. 31–40.

Štítky
Dermatology & STDs Paediatric dermatology & STDs
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