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Cutaneous Amyloidosis. A Review


Authors: E. Sticová 1,2
Authors place of work: Ústav patologie, 3. LF UK a FN Královské Vinohrady, přednosta prof. MUDr. Radoslav Matěj, Ph. D. 1;  Kožní oddělení, Krajská nemocnice Liberec, primář MUDr. Dana Frydrychová 2
Published in the journal: Čes-slov Derm, 98, 2023, No. 1, p. 5-12
Category: Reviews (Continuing Medical Education)

Summary

The term amyloidosis refers to a heterogeneous group of disorders characterized by deposition of misfolded and undegradable proteinaceous material with typical staining properties. Skin is involved in both systemic and localized form of amyloidosis, primary and/or secondary. Amyloid types relevant for cutaneous pathology include amyloid derived from keratin, serum A amyloid, immunoglobulin light chains, β2microglobulin, and transthyretin. The review presents current knowledge about these diseases.

Keywords:

immunohistochemistry – amyloid – AA amyloid – AL amyloid – AK amyloid


Zdroje

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Štítky
Dermatology & STDs Paediatric dermatology & STDs
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