Flow-mediated Dilation (FMD) – Ultrasound Evaluation of Function of Vascular Endothelium in the Population Groups at Risk
Authors:
M. Mráz 1; P. Olexa 2; Ľ. Podracká 1
Authors place of work:
I. Klinika detí a dorastu LF UPJŠ a DFN, Košice
prednostka prof. MUDr. Ľ. Podracká, CSc.
1; Kardiologické oddelenie VÚSCH, Košice
primár MUDr. M. Studenčan, PhD.
2
Published in the journal:
Čes-slov Pediat 2009; 64 (2): 83-88.
Category:
Review
Summary
Cardiovascular diseases are the leading cause of morbidity and mortality in developed world. Their principal underlying mechanism is atherosclerosis which starts in the population at risk already in childhood. Endothelial dysfunction is the first manifestation of the adverse influence that various cardiovascular risk factors have on vessel wall.
As the beginning of atherosclerosis, it is reversible. Hence the current effort to minimize the overall population morbidity and mortality is based on detection of endothelial dysfunction in the young with increased cardiovascular risk. Flow-mediated dilation assessed non-invasively by ultrasound appears as a very promising tool in detection of early changes in vascular wall function.
Key words:
endothelial dysfunction, atherosclerosis, flow-mediated dilation
Zdroje
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Štítky
Neonatology Paediatrics General practitioner for children and adolescentsČlánok vyšiel v časopise
Czech-Slovak Pediatrics
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