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Possibilities of pharmacotherapy of depressive disorder in children and adolescents


Depressive disorder belongs to the mood disorders. It occurs also in children and adolescents. The prevalence of depressive disorder is reported in the literature in approximately 6–12 years-old, around 2.8% and in adolescents 5.6–6.9%. Children are more likely to experience depressive symptoms that do not fulfill the diagnostic criteria for depressive disorder in adult age.

The treatment of depression in children and adolescents consists of a combination of psychopharmacotherapy and psychotherapy. In the treatment the severity of the symptoms of depression should be assessed, as well as the preference of the patient and parents of the patient, the developmental level of the patient, the associated risk factors, and the availability of medical services. Most of the guidelines for the treatment of depression in child psychiatry recommend psychotherapeutic interventions as the first choice. Antidepressant (AD) from the SSRI group fluoxetine should only be considered in patients with moderate to severe depression (especially in adolescents) who do not have access to psychotherapy or do not have a positive response on it. According to the current SPC in Slovakia, only fluoxetine (SSRI) can be used for the treatment of depression. It is allowed from the age of 8 years in the indication of moderate or severe depression.


Authors: J. Trebatická;  J. Šuba
Authors place of work: Klinika detskej psychiatrie, NÚDCH a LFUK, Bratislava, Slovensko
Published in the journal: Čes-slov Pediat 2019; 74 (4): 211-215.
Category:

Summary

Depressive disorder belongs to the mood disorders. It occurs also in children and adolescents. The prevalence of depressive disorder is reported in the literature in approximately 6–12 years-old, around 2.8% and in adolescents 5.6–6.9%. Children are more likely to experience depressive symptoms that do not fulfill the diagnostic criteria for depressive disorder in adult age.

The treatment of depression in children and adolescents consists of a combination of psychopharmacotherapy and psychotherapy. In the treatment the severity of the symptoms of depression should be assessed, as well as the preference of the patient and parents of the patient, the developmental level of the patient, the associated risk factors, and the availability of medical services. Most of the guidelines for the treatment of depression in child psychiatry recommend psychotherapeutic interventions as the first choice. Antidepressant (AD) from the SSRI group fluoxetine should only be considered in patients with moderate to severe depression (especially in adolescents) who do not have access to psychotherapy or do not have a positive response on it. According to the current SPC in Slovakia, only fluoxetine (SSRI) can be used for the treatment of depression. It is allowed from the age of 8 years in the indication of moderate or severe depression.

Keywords:

depressive disorder – pharmacotherapy – children and adolescents


Zdroje

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Štítky
Neonatology Paediatrics General practitioner for children and adolescents

Článok vyšiel v časopise

Czech-Slovak Pediatrics

Číslo 4

2019 Číslo 4
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