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Tularemia – case series


Authors: Slováková Lea 1;  Jendrálová Zuzana 1;  Čepelová Michaela 3;  Cyprová Soňa 3;  Bloomfield Markéta 1,2
Authors place of work: Pediatrická klinika, 1. lékařská fakulta Univerzity Karlovy, Fakultní Thomayerova nemocnice, Praha 1;  Ústav imunologie, 2. lékařská fakulta Univerzity Karlovy, FN Motol, Praha 2;  Klinika dětské hematologie a onkologie, 2. lékařská fakulta Univerzity Karlovy, FN Motol, Praha 3
Published in the journal: Čes-slov Pediat 2023; 78 (Supplementum 1): 24-29.
Category: Case Histories
doi: https://doi.org/10.55095/CSPediatrie2023/029

Summary

Lymphadenopathy is a common symptom in children, yet sometimes it may represent a differential diagnostic pitfall. Tularemia is one of the rare causes of lymphadenopathy in childhood. A clinical suspicion should arise in cases with history of insect bite or animal contact, granulomatous inflammation in biopsy specimen, negative culture results, and/or in cases which fail to respond to first-line antibiotics. Hereby, three cases of children with unexplained lymphadenopathy are presented, highlighting the practical aspects and issues potentially associated with the diagnosis and management of tularemia.

Keywords:

tularemia – Serology – Francisella tularensis – children – ulceroglandular form – lymfadenopathy


Zdroje

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3. Výskyt vybraných hlášených infekcí v České republice, kumulace leden– prosinec 2019. Zprávy Centra epidemiologie a mikrobiologie. Praha: SZÚ 2019; 28(11-12): 423–425.

4. Penn RL. Francisella tularensis (Tularemia). Mendell, Douglas and J.E. Bennet’s Practice of Infectious Diseases. 8th edition. Philadelphia: Elsevier Saunders 2015: 2590–2602.

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6. Centers for Disease Control and Prevention. Tularemia. Dostupné z: https://www.cdc.gov/tularemia

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8. A merican Academy of Pediatrics. 2021 Red Book: Report of the Committee on Infectious Disease – single chapter Tularemia, 32nd edition. Illinois: Academy of Pediatrics 2021.

9. Syrjälä H. Peripheral blood leukocyte counts, erythrocyte sedimentation rate and C-reactive protein in tularemia caused by the type B strain of Francisella tularensis. Infection. 1986; 14 (2): 51–54.

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11. M aurin M. Francisella tularensis, tularemia and serological diagnosis. Front Cell Infect Microbiol 2020; 26 (10): 512090.

Štítky
Neonatology Paediatrics General practitioner for children and adolescents
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