BOTULINUM TOXIN: CURRENT USE IN UROLOGY
Authors:
Vladimír Šámal
Authors place of work:
Urologické oddělení
; Krajská nemocnice Liberec, a. s.
Published in the journal:
Ces Urol 2009; 13(3): 199-206
Category:
Review article
Summary
Botulinum toxin is a presynaptic neuromuscular blocking agent, which induce reversible muscle weakness. From feared poison he changed to intensive researched drug. Many medical disciplines have discovered the indication for treatment. In urology the first experiences is from 1988, when botulinum toxin was used to treat detrusor-sphincter dyssynergia. Nowadays is mostly used to treat neurogenic detrusor overactivity. Effect of treatment can last 6–9 month and continence is restored in about 80% of the patients. Based on actual knowledges is possible to repeat treatment. Influece on decrease of prostatae volume and painful bladder syndrom is still in phase of clinical trials.
Key words:
botulinum toxin, detrusor overactivity, detrusor sphincter dyssynergia, urinary retention, benign prostatic enlargement.
Zdroje
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Štítky
Paediatric urologist Nephrology UrologyČlánok vyšiel v časopise
Czech Urology
2009 Číslo 3
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