Leydig cell tumor of the testis

Česká verzia

Authors: Jakub Szewczyk ¹; Radoslava Tomanová ²; Radek Sýkora ¹; Kateřina Kouřilová ¹; Jan Krhut ¹
Authors place of work: Urologické oddělení, Fakultní nemocnice Ostrava ¹; Ústav patologie, Fakultní nemocnice Ostrava ²
Published in the journal: Ces Urol 2014; 18(1): 65-68
Category: Case report

Summary

We present two case reports of patients with Leydig cell tumors of the testis. These were the only two cases diagnosed at our department since 1989. The first patient had a benign form, and the second patient, an elderly man, had a tumor of uncertain biological character. We describe the diagnosis, treatment and surveillance strategies. In addition, we discuss the possibilities of organ-sparing surgery. We point out the need for monitoring all patients for possible malignant transformation of originally benign forms of this tumour.

Key words:
Leydig cell tumor, stromal tumor, orchiectomy, organ-sparing surgery, uncertain biological character

Zdroje

1. Albers P, Albrecht W, Algaba F, et al. EAU Guidelines on Testicular Cancer, the 2011 update. Eur Urol 2011; 60(2): 304–319.

2. Mati W, Lam G, Dahl C, Thorup Andersen J, Balslev E. Leydig cell tumour – a rare testicular tumour, Int Urol Nephrol 2002; 33: 103–105.

3. Kawaciuk I. Nádory z Leydigových buněk. Urologie 2009; 147: 418.

4. Kim I, Young R, Scully R. Leydig cell tumor of the testis, Am J Surg Pathol 1985; 9(3): 177–192.

5. Dvořáček J, Babjuk M. Nádory ze specifického gonadálního mezodermu, Onkourologie. Praha: Galén, Karolinum 2005; 481–482,506–507.

6. Satish R, Rajesh C, Deepak M. Leydig cell tumor: A case report and review of the literature. Tumori 2002; 88: 75–76.

7. Cheville JC, Sebo TJ, Lager DJ, Bostwick DG, Farrow GM. Leydig Cell Tumor of the Testis, Am J Surg Pathol 1998; 22(11): 1361–1367.

8. Powari M, Kakkar N, Singh SK, Rai RS Jogai S. Malignant Leydig Cell tumour of the Testis. Urol Int 2002; 68: 63–65.

9. Hyršl I, Abrahámová J, Zuntová A, Kawaciuk I, Dušek P. Nádory varlete z Leydigových a Sertoliho buněk. Ces Urol 2005; 9(3): 16–18.

10. Wegner HEH, Dieckmann KP, Herbst H, Andresen R, Miller K. Leydig cell tumor – comparison of results of radical and testis–sparing surgery in a single center., Urol Int 1997; 59: 170–173.

11. Papatsoris AG, Triantafyllidis A, Gekas A, Karamouzis MV, Rosenbaum T. Leydig cell tumor of the testis. new cases and review of the current literature. Tumori 2004; 90: 422–423.

12. Maeda T, Itoh N, Ashi KK, Takahashi A, et al. Elevated serum estradiol suggesting recurrence of Leydig cell tumor nine years after radiál orchiectomy, Int J Urol 2002; 9: 659–661.