A solitary skeletal metastasis in the thumb of a silent bilateral clear cell renal cell carcinoma pT1a in a patient with a sporadic uro‑oncological triplicity

Česká verzia

Authors: Jan Novák ¹; Lukáš Fišer ¹; Robert Jůzek ²; Jan Lesenský ²; Jan Pertlíček ³; Zuzana Špůrková ⁴; Petra Beroušková ⁵; Lubomír Hyršl ¹
Authors place of work: Urologické oddělení, Oblastní nemocnice Kladno, a. s., Kladno ¹; Ortopedická klinika, 1. LF UK a Nemocnice Na Bulovce, Praha ²; Chirurgické oddělení, Oblastní nemocnice Kladno, a. s., Kladno ³; Patologicko‑anatomické oddělení, Nemocnice Na Bulovce, Praha ⁴; Patologicko‑anatomické oddělení, Oblastní nemocnice Kladno, a. s., Kladno ⁵
Published in the journal: Ces Urol 2017; 21(4): 299-304
Category: Case report

Summary

We present a case report of a 72-year old male with a long urological history (prostate adenocarcinoma after radical prostatectomy with rising PSA level and urothelial carcinoma pTa low grade with one recurrence) who underwent reconstructive surgery for a left thumb metastasis of a clear cell renal cell carcinoma. Repeated CT scans showed two tiny lesions in both kidneys during follow-up. Nephron-sparing surgery of the right kidney and left-sided nephroureterectomy in two sessions proved a bilateral clear cell renal cell carcinoma pT1a. The patient underwent genetic analysis by the sequence capture panel CZECANCA targeting 219 susceptibility genes to reveal a highly presumable hereditary cancer syndrome, but no significant mutation was found.

Kez words:
Solitary skeletal metastasis, bilateral kidney cancer, clear cell renal cell carcinoma pT1a, uro-oncological triplicity.

Zdroje

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