Squamous Cell Carcinoma in Situ InvolvingMesonephric Remnants of the Uterine cervix
Karcinóm in situ (CIS) postihujúci mezonefrické zvyšky krčku maternice
Spinocelulárny karcinom in šitu (CIS) postihujúci mezonefrické zvyšky krčku maternice je rarit-ná lézia, ktorej existencia je kontroverzná a diskutovaná. Popísaný je druhý případ tejto lézie. U 40-ročnej pacientky bol v konizáte nájdený CIS v povrchovom epiteli, cervikálnych žliazkach a v niekofkých mezonefrických tubuloch. Mezonefrická povaha tubulov bola podpořená imuno-histochemickou pozitivitou CD10 a vimentinu. CIS v mezonefrických tubuloch napodobňuje inva-zívne lézie, ako sú adenoskvamózny karcinom a adenoidne bazaloidný epitelióm. Kľúčové slová:
Klíčová slova:
mezonefrické zvyšky - uterus - cervix - CIS
Authors:
M. Zámečník
Authors place of work:
Šikl’s Department of Pathology, Faculty Hospital, Charles University, Pilsen, Czech Republic
Published in the journal:
Čes.-slov. Patol., , 2004, No. 3, p. 109-111
Category:
Summary
Squamous cell carcinoma in šitu (CIS) involving mesonephric remnants of the uterine cervix is a very rare lesion, the existence of which is still controversial. A second čase of this lesion is re-ported. It was found in a cone biopsy specimen from an 40-year-old patient. Besides, in surface epithelium and within cervical glands, a structure of CIS was seen in conjunction with mesonephric tubules in deeper cervical stroma. The mesonephric nature of these tubules and of tubule-ap-pearing epithelium within islands of CIS was supported by immunohistochemical positivity for CD10 and vimentin. The lesion strongly simulated invasive carcinomas, such as adenosquamous carcinoma and adenoid basal carcinoma (epithelioma) of the cervix.
Key words:
mesonephric remnants - uterus - cervix - CIS
Štítky
Anatomical pathology Forensic medical examiner ToxicologyČlánok vyšiel v časopise
Czecho-Slovak Pathology
2004 Číslo 3
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