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Expression of CD34 and CD117 in Juxtaglomerular Cell Tumor of Kidney


Authors: Z. Pavlovský;  B. Habanec;  J. Feit;  L. Křen;  S. Čech 1;  M. Charvátová 2
Authors place of work: Ústav patologie FN Brno a LF MU ;  Ústav histologie LF MU 1;  Klinika dětské radiologie FN Brno a LF MU 2
Published in the journal: Čes.-slov. Patol., 44, 2008, No. 3, p. 81-83
Category: Original Article

Summary

Juxtaglomerular cell tumor (JGCT) is an uncommon tumor of the kidney, typically found in young adults. Patients with this tumor suffer from hypertension, hyperaldosteronism and hypokalaemia. Expression of renin and intracytoplasmatic rhomboid crystals or granules in electron microscopic picture are diagnostic features of this tumor. CD34 and CD117 immunoreactivity have recently been reported as helpful markers of JGCT.

Key words:
kidney – juxtaglomerular cell tumor – CD34 and CD117 expression


Zdroje

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9. Robertson, P.W., Klidjian, A., Harding, L.K. et al.: Hypertension due to renin secreting renal tumor. Am. J.Med., 43, 1967, s. 963-976.

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Štítky
Anatomical pathology Forensic medical examiner Toxicology
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