Microvascular density in lymphomas - evaluation methods and clinical impact
Authors:
Pavla Veselá 1; Zbyněk Tonar 2; Ludmila Boudová 1
Authors place of work:
Šiklův ústav patologie, Fakultní nemocnice a Lékařská fakulta UK v Plzni
1; Ústav histologie a embryologie a Biomedicínské centrum LF UK v Plzni
2
Published in the journal:
Čes.-slov. Patol., 51, 2015, No. 2, p. 94-98
Category:
Reviews Article
Summary
In recent years antiangiogenic therapy has become a part of treatment protocols of solid tumors as well as of lymphomas. This is why tumor vascularization has been explored, the most important parameters to describe it being the microvascular density and immunohistochemical assessment of the expression of VEGF (vascular endothelial growth factor) and of its receptors. This review summarizes various methods of assessment of the microvascular density and the prognostic impact of microvascular density in lymphomas.
Keywords:
microvascular density - lymphoma - prognosis
Zdroje
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Štítky
Anatomical pathology Forensic medical examiner ToxicologyČlánok vyšiel v časopise
Czecho-Slovak Pathology
2015 Číslo 2
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