Update on the 2016 WHO classification of tumors of the central nervous system.
Part 2: Embryonal tumors and other tumor groups (except for diffuse gliomas)

Česká verzia

Authors: Josef Zámečník ¹; Boris Rychlý ²; Marián Švajdler ^3,4
Authors place of work: Ústav patologie a molekulární medicíny 2. lékařské fakulty UK a FN v Motole, Praha, Česká republika ¹; Cytopathos s. r. o., Bratislava, Slovenská republika ²; Šiklův ústav patologie, Univerzita Karlova v Praze, Lékařská fakulta v Plzni a Fakultní nemocnice Plzeň, Česká republika ³; Bioptická laboratoř, s. r. o., Plzeň, Česká republika ⁴
Published in the journal: Čes.-slov. Patol., 53, 2017, No. 1, p. 22-28
Category: Reviews Article

Summary

The 2016 revision of the WHO classification of tumors of the central nervous system is a conceptual advance over the 2007 classification system. Similarly to the group of diffuse gliomas, a significant shift in the understanding of the molecular background and tumor biology has recently occurred also in the category of embryonal CNS tumors, especially in medulloblastomas. The classification now incorporates new entities that are defined by both histology and molecular features. Updates in the group of gliomas (except for diffuse gliomas), in the meningeal tumors as well as in the tumors of peripheral nerve sheaths will also be discussed.

Keywords:
WHO classification – meduloblastoma – AT/RT – pleomorphic xanthoastrocytoma – pilocytic astrocytoma – peripheral nerve sheath tumors

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