The Incidence of Nonfermentative Gram-Negative Bacilli in the Environment of the Transplant Unit, Department of Hemato-Oncology, University Hospital Olomouc
Authors:
Matoušková Ivanka 1; Raida Luděk 2; Holý Ondřej 1
Authors place of work:
Hemato-onkologická klinika, Fakultní nemocnice Olomouc
; Ústav preventivního lékařství, Lékařská fakulta Univerzity Palackého v Olomouci
Published in the journal:
Epidemiol. Mikrobiol. Imunol. 61, 2012, č. 4, s. 110-115
Summary
A study entitled „Surveillance of Infectious Complications in Hemato-oncological Patients“ was conducted at the Department of Hemato-Oncology, University Hospital Olomouc from 1 July 2010 to 31 August 2011. During the study period, a total of 63 patients were hospitalized at that department and 33 stem cell transplants were performed, 21 autologous and 12 allogeneic.
Microbial contamination was monitored in indoor air, on selected surfaces, and in health care providers (right hand smear, left and right nostril swabs and scalp hair smear). Gram-negative bacteria detected by culture were identified biochemically. Special attention was paid to nonfermentative Gram-negative bacilli which, based on the recent literature, should be considered as emerging causative agents of hospital infections.
Key words:
nonfermentative Gram-negative bacilli – hemato-oncology patient – resistance to antibiotics and biocides
Zdroje
1. Paitoonpong, L., Neofytos, D., Cosgrove, S. E., Perl., T. M. Infection, Prevention and Control in Hematopoietic Stem Cell – chapter 59; Stosor, V., Hauser, A. R., Flaherty, J. P. Nonfermentative Gram-Negative Bacilli – chapter 35. In Mayhall, C. G. Hospital epidemiology and infection control. Philadelphia: Wolters Kluwer, Lippincott Williams and Wilkins, 2012, Fourt ed., p. 836–872, 520–534.
2. Mackal, C., Fry, T., Gress, R., Peggs, K. et al. Background to hematopoietic cell transplantation, including post transplant immune recovery. Bone Marrow Transplantation, 2009, 44, p. 457–462.
3. Enoch, D. A., Birkett, C. I., Ludlam, H. A. Non-fermentative Gram-negative bacteria. Inter. J. Antimicrobial. Agents, 2007, 29, Suppl. 3, S33–S41.
4. Bieri, S., Roosnek, E., Ozsahin, H., Huguet, S. et al. Outcome and risk factors for late-onset complications 24 months beyond allogeneic hematopoietic stem cell transplantation. Europ. J. Haematol., 2011, 87, p. 138–147.
5. Magauran, C. E., Salgado, C. D. Challenges and Advances in Infection Control of Hematopoietic Stem Cell Transplant Recipients. Infect. Dis – Drug Targets, 2011, 11, p. 18–26.
6. Nagao, M., Iinuma, Y., Igawa, J., Saito, T. et al. Control of an outbreak of carbapenem-resistant Pseudomonas aeruginosa in a haematol-oncology unit. J. Hosp. Infect., 2011,79, p. 49–53.
7. Nyč, O., Matějková, J. Stenotrophomonas maltophilia: Significant contemporary hospital pathogen – review. Folia Microbiol., 2010, 55, 3, p. 286–294.
8. Wilkinson, F. H., Kerr, K. G. Bottled water as a source of multi-resistant Stenotrophomonas and Pseudomonas species for neutropenic patients. Eur. J. Cancer Care, 1998, 7, p. 12–14.
9. Thomas, L., Maillard, J. Y., Lambert, R. J. W., Russell, A. D. Development of resistance to chlorhexidine diacetate in Pseudomonas aeruginosa and the effect of a “residual” concentration. J. Hosp. Infect., 2000, 46, p. 297–303.
10. Spencer, R. C. The emergence of epidemic, multiple-antibiotic-resistant Stenotrophomonas (Xanthomonas) maltophilia and Burkholderia (Pseudomonas) cepacia. J. Hosp. Infect., 1995, 30, p. 453–464.
11. Tada, K., Kurosawa, S., Hiramoto, N., Okinaka, K. et al. Stenotrophomonas maltophilia infection in hematopoietic SCT recipients: high mortality due to pulmonary hemorrhage. Bone Marrow Transplant., 2012 May 28. doi. 10.1038/bmt.2012.87. [Epub ahead of print].
12. Brooke, J. S. Stenotrophomonas maltophilia: an emerging global opportunistic pathogen. Clin. Microbiol. Rev., 2012, 25, 1, p. 2–41.
13. Yeshurun, M., Gafter-Gvili, A., Thelr, M., Keller, N. et al. Clinical characteristics of Stenotrophomonas maltophilia infection in hematopoietic stem cell transplantation recipients: a single center experience. Infection, 2010, 38, p. 211–215.
14. Fihman, V., Le Monnier, A., Corvec, S., Jaureguy, F. et al. Stenotrophomonas maltophilia – The most worrisome threat among unsual non-fermentative gram-negative bacilli from hospitalized patients: A prospective multicenter study. J. Infect., 2012, 64, p. 391–398.
15. Weinstein, R. A., Stamm, W. E., Kramer, L., Corey, L. Pressure monitoring devices. Overlooked source of nosocomial infection. JAMA, 1976, 236, p. 936–938.
16. Ray, M., Lim, D. K. A rare polymicrobial keratitis involving Chryseobacterium meningosepticum and Delftia acidovorans in a cosmetic contact lens wearer. Eye Contact. Lens., 2012 Jan 4. [Epub ahead of print].
17. Chotikanatis, K., Bäcker, M., Rosas-Garcia, G., Hammerschlag, M. R. Recurrent intravascular-catheter-related bacteriemia caused by Delftia acidovorans in a hemodialysis patient. J. Clin. Microbiol., 2011, 49, 9, p. 3418–3421.
18. Kawamura, I, Yagi, T., Hatakeyama, K., Ohkura, T., Ohkura, K., Takahashi, Y., Kojima, S., Hasegawa, Y. Recurrent vascular catheter-related bacteremia caused by Delftia acidovorans with different antimicrobial susceptibility profiles. J. Infect. Chemoter., 2011, 17, p. 111–113.
19. Musso, D., Drancourt, M., Bardot, J., Legre, R. Human infection due to the CDC group IV c-2 bacterium: case report and review. Clin. Infect. Dis., 1994, 18, p. 482–484.
20. Tasbakan, M. S., Yamazhan, T., Aydemir, S., Bacakoglu, F. A case of ventilator-associated pneumonia caused by Cupriavidus pauculus. Mikrobiyol. BUL. 2010, 44, 1, p. 127–131.
21. Duran, R., Vatansever, Ü., Acunas, B., Basaran, Ü. N. Ochrobacterum anthropi bacteremia in a preterm infant with meconium peritonitis. Int. J. Infect. Dis., 2009, 13, e61–e63.
22. Kern, W. V., Oethingerm, M., Kaufhold, A., Rozdzinski, E., Marre, R. Ochrobactrum anthropi bacteriemia: report of four cases and short review. Infection, 1993, 21, 5, p. 306–310.
23. Ezzedine, H., Mourad, M., Van Ossel, C., Logghe, C., Squifflet, J. P., Renault, F., Wauters, G., Gigi, J., Wilmitte, L., Haxhe, J. J. An outbreak of Ochrobactrum anthropi in five organ transplant patients. J. Hosp. Infect., 1994, 27, 1, p. 35–42.
24. Sachdeva, L. D., Bardhan, P. N. Bacteriological study of an Alcaligenes faecalis strain: a food poisoning epidemic. Indian. J. Pathol. Bacteriol., 1963, 37, p. 513–514.
25. Tai, T. Y., Chin, W. T., Wang, F., Hsi, M. S. Bacillus Alcaligenes infections. A clinical analysis of 33 cases. Chin. Med. J. (Engl), 1963, 82, p. 423–431.
26. Zbinden, R., von Grevenitz, A. Actinobacillus, Capnocytophaga, Eikenella, Kingella, Pasteurella, and Other Fastidiuos Rods – chapter 33. In Versalovic J. ed. Manual of Clinical Microbiology. Washington, DC: ASM PRESS, 2011, 10th ed., p. 574–584.
27. Slonim, A., Steiner, M., Yagupsky, P. Immune Response to Invasive Kingella kingae Infections, Age-Related Incidence of Disease, and Levels of Antibody to Outer-Membrane Proteins. CID 2003, 15, p. 521–527.
28. Dubnov-Raz, G., Scheuerman, O., Chodick, G., Finkelstein, Y., Samra, Z., Ben-Zion, G. Invasive Kingella kingae Infections in Children: Clinical and Laboratory Characteristics. Pediatrics, 2008, 122, p. 1305–1309.
29. Kim, Y. H., Panday, V., Reilly, C. Isolation of Kingella denitrificans a corneal ulcer. Cornea, 2011, 30, 4, p. 472–473.
30. Rajanna, D. M., Manickavasagam, J., Jewes, L., Capper, R. Retropharyngeal abscess from an unsual organism-Kingella denitrificans-in a patient on low-dose methotrexate. Ear Nose Throat. J., 2011, 90, 7, E15–17.
31. Playford, E. G., Craig, J. C., Iredell, J. R. Carbapenem-resistant Acinetobacter baumanii in intensive care unit patients: risk factors for acquisition, infection and their consequences. J. Hosp. Infect., 2007, 65, p. 204–211.
32. Bassetti, M., Ginocchio, F., Mikulska, M. New treatment options against gram-negative organism. Critical Care, 2011, 15: 215. http://ccforum.com/content/15/2/215.
33. Carter, J. E., Evans, T. N. Clinically Significant Kluyvera Infections. Am. J. Clin. Pathol., 2005, 123, p. 334–338.
34. Isozaki, A., Shiraim, K., Mimura, S., Takahashi, M., Furushima, W., Kawano, Y. A case of urinary tract infection caused by Kluyvera ascorbata in an infant: case report and review of the literature. J. Infect. Chemother., 2010, 16, p. 436–438.
35. Simöes, L. C., Lemos, M., Pereira, A. M., Abreu, A. C. et al. Persister cells in a biofilm treated with a biocide. Biofouling 2011, 27, p. 403-11.
Štítky
Hygiene and epidemiology Medical virology Clinical microbiologyČlánok vyšiel v časopise
Epidemiology, Microbiology, Immunology
2012 Číslo 4
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