Potential problem of the co-occurrence of pandemic COVID-19 and seasonal influenza

Česká verzia

Authors: R. Mezencev ¹; C. Klement ^2,3; S. Dluholucký ^4,5
Authors place of work: Georgia Institute of Technology, Atlanta GA, USA ¹; Regionálny úrad verejného zdravotníctva, Banská Bystrica, Slovenská republika ²; Fakulta verejného zdravotníctva, Slovenská zdravotnícka univerzita, Bratislava, Slovenská republika ³; Detská fakultná nemocnica, Slovenská zdravotnícka univerzita, Bratislava, Slovenská republika ⁴; Fakulta zdravotníctva, Slovenská zdravotnícka univerzita, Bratislava, Slovenská republika ⁵
Published in the journal: Epidemiol. Mikrobiol. Imunol. 70, 2021, č. 1, s. 68-71
Category: Short Communication

Summary

In times of COVID-19 pandemics, the upcoming period of the year when influenza activity usually increases in the Northern Hemisphere brings new medical and public health challenges. These challenges include the risk of mixed infections and/or a possible collision of the two epidemics (“twindemia”) with a potentially serious impact on individual health and public health. In this report, we discuss the results of the published studies and conclude that the catastrophic collision of the seasonal influenza and COVID-19 epidemics is unlikely when efficient non-pharmaceutical public health measures are applied to control or mitigate the spread of the COVID-19 epidemic. This conclusion is supported by several lines of evidence, including the extremely low seasonal influenza activity registered in the Southern Hemisphere in 2020. On the other hand, the existence of mixed SARS-CoV-2 and influenza virus infections has been demonstrated in humans. The continuing uncertainty about the occurrence and potential severity of these mixed infections emphasizes the importance of seasonal influenza vaccination in the current epidemiological situation and raises the need to: (i) ensure vaccine availability, (ii) facilitate access to safe seasonal influenza vaccination under the conditions of the ongoing COVID-19 epidemic, and (iii) promote the vaccine to the public.

Keywords:

COVID-19 – influenza – twindemia – viral interference– immunization

Zdroje

1. Sun J, He W-T, Wang L, et al. COVID-19: epidemiology, evolution, and cross-disciplinary perspectives. Trends Mol Med, 2020;26(5):483–495.

2. Dong E, Du H, Gardner L. An interactive web-based dashboard to track COVID-19 in real time. The Lancet Infect Dis, 2020;20(5):533–534.

3. Jaklevic MC. Flu Vaccination Urged During COVID-19 Pandemic. JAMA, 2020;324(10):926–927.

4. Belongia EA, Osterholm MT. COVID-19 and flu, a perfect storm. Science, 2020;368(6496):1163–1163.

5. Singh B, Kaur P, Reid R-J, et al. COVID-19 and Influenza Co-Infection: Report of Three Cases. Cureus, 2020;12(8):e9852–e9852.

6. Miatech JL, Tarte NN, Katragadda S, et al. A case series of coinfection with SARS-CoV-2 and influenza virus in Louisiana. Respir Med Case Rep, 2020;31:101214.

7. Garcia-Vidal C, Sanjuan G, Moreno-García E, et al. Incidence of co-infections and superinfections in hospitalized patients with COVID-19: a retrospective cohort study. Clin Microbiol Infect, 2020;S1198-743X(20)30450-X.

8. Lansbury L, Lim B, Baskaran V, Lim WS. Co-infections in people with COVID-19: a systematic review and meta-analysis. J Inf, 2020;81(2):266–275.

9. Lai C-C, Wang C-Y, Hsueh P-R. Co-infections among patients with COVID-19: The need for combination therapy with non-anti-SARS--CoV-2 agents? J Microbiol Immunol Infect, 2020;53(4):505–512.

10. Ding Q, Lu P, Fan Y, et al. The clinical characteristics of pneumonia patients coinfected with 2019 novel coronavirus and influenza virus in Wuhan, China. J Med Virol, 2020;92(9):1549–1555.

11. Nowak MD, Sordillo EM, Gitman MA-O, Paniz Mondolfi AA-O. Co-infection in SARS-CoV-2 infected Patients: Where Are Influenza Virus and Rhinovirus/Enterovirus? J Med Virol, 2020; 30:10.1002/jmv.25953.

12. Wu A, Mihaylova VT, Landry ML, Foxman EF. Interference between rhinovirus and influenza A virus: a clinical data analysis and experimental infection study. Lancet Microbe, 2020;1(6):e254–e262.

13. Castillo EM, Coyne CJ, Brennan JJ, Tomaszewski CA. Rates of coinfection with other respiratory pathogens in patients positive for coronavirus disease 2019 (COVID-19). J Am Coll Emerg Physicians Open, 2020;1(4):592–596.

14. Riou J, Althaus CL. Pattern of early human-to-human transmission of Wuhan 2019 novel coronavirus (2019-nCoV), December 2019 to January 2020. Eurosurveillance, 2020;25(4):2000058.

15. Sun J, Shi Z, Xu H. Non-pharmaceutical interventions used for COVID-19 had a major impact on reducing influenza in China in 2020. J Travel Med, 2020;Apr 24;taaa064.

16. Soo RJJ, Chiew CJ, Ma S, et al. Decreased Influenza Incidence under COVID-19 Control Measures, Singapore. Emerg Infect Dis, 2020;26(8):1933–1935.

17. Olsen SJ, Azziz-Baumgartner E, Budd AP, et al. Decreased Influenza Activity During the COVID-19 Pandemic – United States, Australia, Chile, and South Africa, 2020. Am J Transplant, 2020;20(12):3681–3685.

18. Zipfel CM, Bansal S. Assessing the interactions between COVID-19 and influenza in the United States. medRxiv, 2020;2020.03.30.20047993.

19. Hale T, Petherick A, Phillips T, Webster S. Variation in government responses to COVID-19 [online]. Version 9.0: Blavatnik School of Government working paper, 2020 [cit.2020-06-12]. Dostupný na www:<http://www.bsg.ox.ac.uk/sites/default/files/2020-11/BSG-WP-2020-032-v9.pdf>.

20. Australia tracks 35% jump in flu vaccine shipments [online]. 2020-01-09 [cit. 2020-06-12]. Dostupný na www: https://www.biopharma-reporter.com/Article/2020/09/01/Australia-tracks-35-jump-in-flu-vaccine-shipments.

21. Sullivan SG, Arriola CS, Bocacao J, et al. Heterogeneity in influenza seasonality and vaccine effectiveness in Australia, Chile, New Zealand and South Africa: early estimates of the 2019 influenza season. Euro Surveill, 2019;24(45):1900645.

22. Cohen M. South Africa is short on flu vaccine, compounding coronavirus fight [online]. 2020-28-03 [cit. 2020-06-12]. Dostupný na www: < https://www.bloomberg.com/news/articles/2020-03-28/south-africa-says-coronavirus-cases-rise-to-1-187-from-1-170>.

23. Weekly U.S. Influenza Surveillance Report (FluView) [online]. [cit. 2020-06-12]. Dostupný na www: https://www.cdc.gov/flu/weekly/overview.htm.

24. Havlickova M, Druelles S, Jirincova H, et al. Circulation of influenza A and B in the Czech Republic from 2000-2001 to 2015-2016. BMC Infect Dis, 2019;19(1):160.

25. Paget J, Caini S, Cowling B, et al. The impact of influenza vaccination on the COVID-19 pandemic? Evidence and lessons for public health policies. Vaccine, 2020;38(42):6485–6486.

26. Wolff GG. Influenza vaccination and respiratory virus interference among Department of Defense personnel during the 2017–2018 influenza season. Vaccine, 2020; 38(2):350–354.

27. Wolff GG. Letter to the Editor. Vaccine, 2020;38(30):4651–4651.

28. Bloom BR, Nowak GJ, Orenstein W. “When Will We Have a Vaccine?” – Understanding Questions and Answers about Covid-19 Vaccination. N Engl J Med, 2020;383(23):2202–2204.