Diabetes mellitus and secondary immunodeficiency
Authors:
Daniela Kantárová 1,2; Mojmír Vrlík 2; Ivana Ságová 1; Dana Prídavková 1; Peter Galajda 1; Marián Mokáň 1
Authors place of work:
I. interná klinika Jesseniovej LF UK a UNM, Martin
1; Martinské centrum imunológie, Martin
2
Published in the journal:
Forum Diab 2016; 5(3): 146-150
Category:
Topic
Summary
Type 1 and type 2 diabetes mellitus is a complex disorder which affects multiple organs and organ systems, not excluding the immune system. It is quite frequently caused by secondary immunodeficiency – therefore it affects mechanisms of both non-specific (chemotaxis, phagocytosis) and specific immunity (generation and maturation of B- and T-lymphocytes). Diabetes is associated with an increased incidence of infectious diseases – mainly those of the urogenital tract, skin and airways. The course of infections in diabetics is more serious, involving more complications, requiring aggressive treatment and lastly it is associated with higher mortality.
Key words:
diabetes mellitus – complicated infections in patients with diabetes mellitus – non-specific immunity – secondary immunodeficiency – specific immunity
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Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Forum Diabetologicum
2016 Číslo 3
Najčítanejšie v tomto čísle
- Diabetes mellitus and secondary immunodeficiency
- Chronic obstructive pulmonary disease, metabolic syndrome and diabetes mellitus
- An infection of the urogenital tract in female patients with diabetes
- Assessment of the development of head and neck infections – comparison of cohorts of patients with and without diabetes mellitus