Insulin therapy during pregnancy
Authors:
Silvia Dókušová 1; Emil Martinka 1; Karol Dókuš 2
Authors place of work:
Diabetologické oddelenie, NEDÚ, Ľubochňa
1; Gynekologicko-pôrodnícka klinika JLF UK a UNM, Martin
2
Published in the journal:
Forum Diab 2017; 6(2): 88-90
Category:
Topic
Summary
Pregnant women with diabetes mellitus are at increased risk of serious complications during pregnancy, in regard to the fetus, newborn and mother, which are mainly associated with insufficient diabetes control. The reaching of intensive metabolic control is often limited by occurrence of hypoglycemia. Furthermore, pregnancy entails specific physiologically and quickly changing requirements regarding insulin need. In recent years, significant progress has been achieved regarding the methods and effectiveness of monitoring glycemia, introduction of new insulin analogues and development of modern practices of insulin use, in particular the insulin pump. The paper brings an overview of insulin preparations currently used in clinical practice and possibilities of their utilization in pregnancy.
Key words:
diabetes mellitus, glycemia monitoring, hypoglycemia, insulin analogues, pregnancy
Received:
19. 4. 2017
Accepted:
2. 5. 2017
Zdroje
1. 1. Vargas R, Repke JT, Ural SH. Type 1 diabetes mellitus and pregnancy. Rev Obstetr Gynecol 2010; 3(3): 92–100.
2. Holmes VA, Young IS, Patterson CC et al. Optimal glycemic control, pre-eclampsia, and gestational hypertension in women with type 1 diabetes in the diabetes and pre-eclampsia intervention trial. Diabetes Care 2011;34(8):1683–1688. Dostupné z DOI: <http://dx.doi.org/10.2337/dc11–0244>.
3. Ringholm L, Pedersen-Bjergaard U et al. Hypoglycemia in pregnant women with type 1 diabetes: clinical features and management. Diabetic Hypoglycemia 2011; 3(3): 3–7.
4. Keating GM. Insulin detemir: a review of its use in the management of diabetes mellitus. Drugs 2012; 72(17): 2255–2287. Dostupné z DOI: <http://dx.doi.org/10.2165/11470200–000000000–00000>.
5. Durnwald CP, Landon MB. Insulin analogues in the management of the pregnancy complicated by diabetes mellitus. Curr Diab Rep 2011; 11(1): 28–34. Dostupné z DOI: <http://dx.doi.org/10.1007/s11892–010–0160–0>.
6. Mathiesen ER, Hod M, Ivanisevic M et al. Maternal efficacy and safety outcomes in a randomized, controlled trial comparing insulin detemir with NPH insulin in 310 pregnant women with type 1 diabetes. Diabetes Care 2012; 35(10): 2012–2017.
7. Hod M, Mathiesen ER, Jovanovic L et al. A randomized trial comparing perinatal outcomes using insulin detemir or neutral protamine Hagedorn in type 1 diabetes. J Matern Fetal Neonatal Med 2014; 27(1): 7–13. Dostupné z DOI: <http://dx.doi.org/10.3109/14767058.2013.799650>.
8. Golden SH, Sapir T. Methods for insulin delivery and glucose monitoring in diabetes: summary of a comparative effectiveness review. J Manag Care Pharm 2012; 18(9): 1–17.
9. Wender-Ozegowska E, Zawiejska A, Ozegowska K et al. Multiple daily injections of insulin versus continuous subcutaneous insulin infusion for pregnant women with type 1 diabetes. Aust N Z J Obstet Gynaecol 2013; 53(2): 130–135. Dostupné z DOI: <http://dx.doi.org/10.1111/ajo.12027>.
Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Forum Diabetologicum
2017 Číslo 2
Najčítanejšie v tomto čísle
- Overinsulinization – the frequent cause of unsatisfactory glycemic control: case reports
- Insulin in the therapeutic scheme for type 2 diabetes mellitus
- Insulin therapy during pregnancy
- Factors conducive to optimal control of type 1 diabetes mellitus in childhood and adolescence