Ten years of treatment of type 2 diabetes mellitus by gliflozins
Authors:
Peter Galajda; Matej Samoš; Tomáš Bolek; Simona Horná; Marián Mokáň
Authors place of work:
I. interná klinika JLF UK a UNM, Martin
Published in the journal:
Forum Diab 2023; 12(2): 76-83
Category:
Summary
Sodium-glucose co-transporter 2 (SGLT2) inhibitors, gliflozins are a modern class of diabetic medications which are used ten years in the treatment of type 2 diabetes mellitus. Apart from good glycemic control, low risk of hypoglycemia and weight loss, gliflozins have been shown to provide significant cardiovascular and nephroprotective benefit in patients with type 2 diabetes mellitus. Adverse side effects include increased risk of urinary infections, mainly vaginal candidosis euglycemic ketoacidosis, volume depletion with hypotension, which are considered to be a class effect of gliflozins. According to international standards gliflozins can be indicated such drugs of first choice in the treatment of type 2 diabetic patients with high cardiovascular risk.
Keywords:
gliflozins – adverse effect – cardiovascular and nephroprotective benefit – euglycemic ketoacidosis – sodium-glucose co-transporter 2 (SGLT2) inhibitors- type 2 diabetes mellitus – urinary infections – vaginal candidosis – volume depletion with hypotension
Zdroje
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Štítky
Diabetology Endocrinology Internal medicineČlánok vyšiel v časopise
Forum Diabetologicum
2023 Číslo 2
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