Corticosteroids as a treatment of rheumatoid arthritis

Česká verzia

Authors: K. Trnavský
Authors place of work: Ředitel: MUDr. Zdeněk Hadra ; Vedoucí lékař: prof. MUDr. K. Trnavský, DrSc. ; Institut postgraduálního vzdělávání ve zdravotnictví, Praha ; Arthrocentrum Praha
Published in the journal: Prakt. Lék. 2009; 89(3): 134-135
Category: Of different specialties

Summary

Corticosteroids have their firm place in the pharmacotherapy of rheumatoid arthritis. They are administered in high doses for suppression of acute exacerbation of the disease. Low-dose (between 5–7.5 mg of prednisone daily) in the combination with disease modifying drugs (like methotrexate, sulfasalazine) is the most widely used form of corticosteroids administration in 30 % of patients. Corticosteroids in low-dose are able to decrease the radiographic progression of joint destruction. Low-dose of corticosteroids are generally well tolerated and no new osteoporotic fractures were found in the treated patients.

Key words:
Rheumatoid arthritis, corticosteroids therapy.

Zdroje

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