Significant aortic stenosis in routine clinical practice

Česká verzia

Authors: J. Vondrák; P. Vojtíšek
Authors place of work: Kardiologické oddělení ; Primář: MUDr. Petr Vojtíšek, CSc. ; Pardubická krajská nemocnice a. s., Pardubice
Published in the journal: Prakt. Lék. 2012; 92(5): 280-283
Category: Of different specialties

Summary

The aim of our study
was to obtain baseline characteristics of the patients referred to our centre for overall evaluation for significant aortic stenosis. We analysed 100 consecutive patients comprehensively examined for significant aortic stenosis between March 2009 and August 2010. The average age was 71 years, males predominated (59%). The dominant symptoms were dyspnoea and chest pain. Major cardiovascular risk factors associated with aortic stenosis were arterial hypertension, hyperlipidaemia, diabetes mellitus and smoking habits. Significant coronary disease was diagnosed in 49 cases. Echocardiography revealed bicuspid aortic valve in 26 patients, in 19 we were unable to determine the number of cusps. The mean indexed aortic valve orifice area was 0.43 cm²/m², left ventricular EF 59%. Interventricular septal thickness average 12 mm, estimated systolic pulmonary artery pressure 46 mm Hg, the average size of ascending aorta was 35.8 mm. Patients with bicuspid aortic valve were younger and had larger ascending aorta (40 vs. 34 mm). There was no other difference in the tested parameters between these groups. 74 patients underwent valvular correction. Biological prosthesis was implanted most frequently, in two cases the valve was implanted in a percutaneous approach. We checked all patients’ health status by telephone in December 2010. Patients who underwent surgery indicated an improvement in their symptoms. Nobody died in this group. In contrast, patients treated conservatively were more symptomatic and we recorded 4 deaths. In summary aortic stenosis is associated with an adverse cardiovascular risk profile. Half of patients with severe aortic stenosis have significant stenosis of coronary arteries. Patients with bicuspid aortic valve are younger, with a tendency to dilatation of the ascending aorta. The only way to reduce symptoms and improve prognosis is aortic valve replacement.

Key words:
aortic stenosis, coronary disease, valvular correction

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